4-(Trifluoromethyl)-5,6,7,8-tetrahydroquinazoline-2-thiol CAS 318258-18-3
| CAS No. | 318258-18-3 |
| Molecular Formula | C9H9F3N2S |
| Molecular Weight | 234.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-(Trifluoromethyl)-5,6,7,8-tetrahydroquinazoline-2-thiol (C9H9F3N2S) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
4-(Trifluoromethyl)-5,6,7,8-tetrahydroquinazoline-2-thiol (CAS 318258-18-3) is a high-purity analytical reference standard with the molecular formula C9H9F3N2S and a molecular weight of 234.24 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-(Trifluoromethyl)-5,6,7,8-tetrahydroquinazoline-2-thiol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H9F3N2S |
| Molecular Weight | 234.24 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Trifluoromethyl Standards
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