1-Chloroacetylpiperidine-4-carboxylic acid CAS 318280-69-2
| CAS No. | 318280-69-2 |
| Molecular Formula | C8H12ClNO3 |
| Molecular Weight | 205.64 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1-Chloroacetylpiperidine-4-carboxylic acid (CAS 318280-69-2), molecular formula C8H12ClNO3 and molecular weight 205.64 g/mol, is a CATO reference standard with documented purity and traceability.
1-Chloroacetylpiperidine-4-carboxylic acid (C8H12ClNO3) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 1-Chloroacetylpiperidine-4-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H12ClNO3 |
| Molecular Weight | 205.64 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- 1-(Chlorocarbonyl)piperidin-4-yl acetate (CAS 496052-32-5)
- 1-Phenyl-1H-pyrrole-3-carbonyl chloride (CAS 220968-56-9)
- 1-(7-Chloroquinolin-4-yl)ethanone (CAS 89770-25-2)
- 2-(Chloromethyl)-4-(pyridin-3-yl)pyrimidine (CAS 944899-71-2)
- 4,4'-Bi-4H-1,2,4-triazole (CAS 16227-15-9)
- 3-Methoxy-4-((1-phenyl-1H-tetrazol-5-yl)oxy)benzaldehyde (CAS 724755-47-9)
- 6-nitroimidazo[1,2-a]pyridine-8-carboxylic acid (CAS 1352723-56-8)
- 3-Methoxybenzoic Acid (CAS 586-38-9)
- 2-(4-(3,4-Dichlorophenyl)piperazine-1-carbonyl)cyclopropane-1-carboxylic acid (CAS 866150-83-6)
- 3-(Triphenylsilyl)propan-1-ol (CAS 2509-34-4)
- 10-Benzyl-9,10-dihydroacridine (CAS 87742-33-4)
- Methyl (2S,4S)-2-methylpiperidine-4-carboxylate (CAS 1932621-09-4)
- 4-(3-Bromothiophen-2-yl)-2-(1H-pyrrol-1-yl)pyrimidine (CAS 860788-64-3)
- Semaglutide Impurity 163 (x TFA Salt) (CAS CATO-C4X-2226163)
Why CATO?
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