Doxapram EP Impurity A CAS 3192-64-1
| CAS No. | 3192-64-1 |
| Molecular Formula | C20H22ClNO |
| Molecular Weight | 327.85 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Doxapram EP Impurity A meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Doxapram EP Impurity A (CAS 3192-64-1) is a certified pharmaceutical impurity reference standard with the molecular formula C20H22ClNO and a molecular weight of 327.85 g/mol.
Structurally, Doxapram EP Impurity A (C20H22ClNO) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 10.0, corresponding to approximately 10 ring(s) or double-bond equivalent(s). With a molecular weight of 327.85 g/mol, it falls into the moderately-high-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C20H22ClNO |
| Molecular Weight | 327.85 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Doxapram Standards
- Doxapram Impurity 20 (CAS CATO-C4X-197320)
- Doxapram Impurity 21 (CAS 14327-53-8)
- Doxapram Impurity 7 (CAS 3471-97-4)
- Doxapram Impurity 35 (CAS CATO-C4X-197335)
- Doxapram Impurity 38 (CAS CATO-C4X-197338)
- Doxapram Impurity 8 (CAS CATO-C4X-19738)
- Doxapram Impurity 6 (CAS CATO-C4X-19736)
- Doxapram Impurity 13 (CAS CATO-C4X-197313)
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