4-Bromo-3-(trifluoromethyl)phenol CAS 320-49-0
| CAS No. | 320-49-0 |
| Molecular Formula | C7H4BrF3O |
| Molecular Weight | 241.01 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO supplies 4-Bromo-3-(trifluoromethyl)phenol (CAS 320-49-0), a certified reference material (molecular formula C7H4BrF3O, MW 241.01 g/mol) for analytical method development and quality control.
The molecular framework of 4-Bromo-3-(trifluoromethyl)phenol (C7H4BrF3O) is characterized by a hydroxyl group, an ether linkage, fluorine/bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H4BrF3O |
| Molecular Weight | 241.01 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F/Br-containing |
Related Bromo Standards
- 3-Bromo-5-(trifluoromethyl)phenol (CAS 1025718-84-6)
- 4-Bromo-6-methyl-2-(trifluoromethyl)pyrimidine (CAS 1100767-01-8)
- 4-Bromo-2-methyl-6-(trifluoromethyl)pyrimidine (CAS 1100767-02-9)
- 5-Bromo-4-methyl-2-(trifluoromethyl)pyrimidine (CAS 1100767-04-1)
- 5-Bromo-2-(trifluoromethyl)phenol (CAS 1121585-15-6)
- 4-Bromo-6-(trifluoromethyl)pyridin-3-amine (CAS 1196152-12-1)
- 5-Bromo-2-trifluoromethyl-pyridin-3-ylamine (CAS 1211533-18-4)
- 2-Bromo-3-(trifluoromethyl)phenol (CAS 1214323-39-3)
Recommended Standards
- 4-Bromo-2-(trifluoromethyl)phenol (CAS 50824-04-9)
- 5-(Bromomethyl)-2-(trifluoromethyl)pyrimidine (CAS 198404-35-2)
- 4-Bromo-2-(difluoromethoxy)-1-fluorobenzene (CAS 954235-78-0)
- 5-Bromo-4-(trifluoromethyl)pyridin-2-amine, 97% (CAS 944401-56-3)
- {4-[(dimethyl-1,2-oxazol-4-yl)methoxy]phenyl}methanamine (CAS 1178816-89-1)
- (5-methoxy-1-methyl-1H-1,3-benzodiazol-2-yl)methanamine (CAS 1017357-82-2)
- 5-Methyl-dCTP (aqueous solution) (CAS 22003-12-9)
- Revefenacin (CAS 864750-70-9)
- (3-Chloro-but-2-enyl)-(1-phenyl-ethyl)-amine hydrochloride 1052527-72-6 8176AC C12H17Cl2N (CAS 1052527-72-6)
- 4-HYdroxy-n-[(4-methoxyphenyl)methyl]benzamide (CAS 1019441-41-8)
- 2-[Na-Benzoylbenzoicamido-N6-(6-biotinamidocaproyl)-L-lysinylamido]ethyl Methanethiosulfonate (CAS 910036-44-1)
- 3-Amino-4,6-dichloropyridine-2-carboxylic Acid (CAS 1073182-87-2)
- Salmeterol Impurity 6 (CAS 75906-36-4)
- DAPK Substrate Peptide (CAS 386769-53-5)
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