2,5-Bis(trifluoromethyl)-1,4-dichlorobenzene CAS 320-55-8
| CAS No. | 320-55-8 |
| Molecular Formula | C8H2Cl2F6 |
| Molecular Weight | 283.00 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2,5-Bis(trifluoromethyl)-1,4-dichlorobenzene is closely related to fluorine/chlorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
2,5-Bis(trifluoromethyl)-1,4-dichlorobenzene (CAS 320-55-8), molecular formula C8H2Cl2F6 and molecular weight 283.00 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2,5-Bis(trifluoromethyl)-1,4-dichlorobenzene (C8H2Cl2F6) is characterized by fluorine/chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2,5-Bis(trifluoromethyl)-1,4-dichlorobenzene meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H2Cl2F6 |
| Molecular Weight | 283.00 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F/Cl-containing |
Related Bis Standards
- 2,4-Bis(trifluoromethyl)-1,5-dichlorobenzene (CAS 116412-77-2)
- 1,2-Bis(trifluoromethyl)-3,4-dichlorobenzene (CAS 1221272-78-1)
- 1,4-Bis(trifluoromethyl)-2,6-dichlorobenzene (CAS 1805517-15-0)
- 2-[3-(Trifluoromethyl)phenoxy]pyridine-5-boronic acid (CAS 2096332-23-7)
- 3,5-Bis-trifluoromethyl-4-bromo-1H-pyrazole (CAS 1376710-07-4)
- 4-((6-(Trifluoromethyl)pyridin-2-yl)oxy)benzoic acid (CAS 1086379-75-0)
- 2-Oxo-1-(3-(trifluoromethyl)phenyl)-1,2-dihydropyridine-3-carboxylic acid (CAS 1272758-11-8)
- 3-{[6-(Trifluoromethyl)pyridin-2-yl]oxy}benzoic acid (CAS 1287218-58-9)
Recommended Standards
- 2,3-Dichloro-1,4-bis(trifluoromethyl)benzene (CAS 887268-06-6)
- Monophenyltriethyltin (CAS 878-51-3)
- 1,2-Dichloro-4,5-bis(trifluoromethyl)benzene (CAS 320-22-9)
- 36132-08-8 5,7-Dibromo-1H-indole 5,7-Dibromoindole (CAS 36132-08-8)
- 3-(difluoromethyl)-1-methyl-pyrazole-4-carbonyl chloride (CAS 141573-96-8)
- Butyl Acetate (CAS 123-86-4)
- Tert-butyl 6-(aminomethyl)-2,2-dimethylmorpholine-4-carboxylate (CAS 1416440-07-7)
- 2＇-Methoxyacetophenone (CAS 579-74-8)
- (3-Methylphenyl)oxirane (CAS 20697-03-4)
- Methyl β-[(2-chloroacetyl)amino]-2-thiophenepropanoate (CAS 1153928-34-7)
- 4-Methyl-1-nitrosopiperidine (CAS 15104-03-7)
- N-Benzyl-2-hydroxyethane-1-sulfonamide (CAS 149944-36-5)
- 6,8-Difluorothiochroman-4-one (CAS 1097779-72-0)
- Liraglutide (13-21) TFA Salt (CAS CATO-C4X-19928)
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