4-Phenyl-6-[(propan-2-yl)amino]-2-(pyridin-4-yl)pyrimidine-5-carbonitrile CAS 320417-90-1

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-Phenyl-6-[(propan-2-yl)amino]-2-(pyridin-4-yl)pyrimidine-5-carbonitrile.

CATO supplies 4-Phenyl-6-[(propan-2-yl)amino]-2-(pyridin-4-yl)pyrimidine-5-carbonitrile (CAS 320417-90-1), a certified reference material (molecular formula C19H17N5, MW 315.37 g/mol) for analytical method development and quality control.

The molecular framework of 4-Phenyl-6-[(propan-2-yl)amino]-2-(pyridin-4-yl)pyrimidine-5-carbonitrile (C19H17N5) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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