(3Z)-N-(2,4-Difluorophenyl)-3-{[(4-nitrophenyl)methoxy]imino}propanamide CAS 320418-05-1

Purity 97%+In StockPharmaceutical Standards
CAS No.320418-05-1
Molecular FormulaC16H13F2N3O4
Molecular Weight349.29 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

(3Z)-N-(2,4-Difluorophenyl)-3-{[(4-nitrophenyl)methoxy]imino}propanamide CAS 320418-05-1 chemical structure

Description

The occurrence of (3Z)-N-(2,4-Difluorophenyl)-3-{[(4-nitrophenyl)methoxy]imino}propanamide is closely related to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

(3Z)-N-(2,4-Difluorophenyl)-3-{[(4-nitrophenyl)methoxy]imino}propanamide (CAS 320418-05-1), molecular formula C16H13F2N3O4 and molecular weight 349.29 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of (3Z)-N-(2,4-Difluorophenyl)-3-{[(4-nitrophenyl)methoxy]imino}propanamide (C16H13F2N3O4) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), (3Z)-N-(2,4-Difluorophenyl)-3-{[(4-nitrophenyl)methoxy]imino}propanamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC16H13F2N3O4
Molecular Weight349.29 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)11.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentF-containing
Nitrogen Atoms3

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