2-(2,4,5-Trioxo-3-{[3-(trifluoromethyl)phenyl]methyl}imidazolidin-1-yl)acetonitrile CAS 320422-99-9
| CAS No. | 320422-99-9 |
| Molecular Formula | C13H8F3N3O3 |
| Molecular Weight | 311.22 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-(2,4,5-Trioxo-3-{[3-(trifluoromethyl)phenyl]methyl}imidazolidin-1-yl)acetonitrile (CAS 320422-99-9) is a high-purity analytical reference standard with the molecular formula C13H8F3N3O3 and a molecular weight of 311.22 g/mol.
The molecular framework of 2-(2,4,5-Trioxo-3-{[3-(trifluoromethyl)phenyl]methyl}imidazolidin-1-yl)acetonitrile (C13H8F3N3O3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 2-(2,4,5-Trioxo-3-{[3-(trifluoromethyl)phenyl]methyl}imidazolidin-1-yl)acetonitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C13H8F3N3O3 |
| Molecular Weight | 311.22 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Trioxo Standards
- 1,1,3-Trioxo-2-(oxolan-2-ylmethyl)-2,3-dihydro-1,2-benzothiazole-6-carboxylic acid (CAS 1040074-58-5)
- 2-(2,4,5-Trioxo-3-(2,4,6-trimethylbenzyl)imidazolidin-1-yl)acetic acid (CAS 303986-47-2)
- 2-(2,4,5-Trioxo-3-(3-(trifluoromethyl)benzyl)imidazolidin-1-yl)acetamide (CAS 320422-81-9)
- 2-(2,4,5-Trioxo-3-(4-(trifluoromethyl)benzyl)imidazolidin-1-yl)acetic acid (CAS 179412-71-6)
- Ethyl 2-{2,4,5-trioxo-3-[(2,4,6-trimethylphenyl)methyl]imidazolidin-1-yl}acetate (CAS 303986-40-5)
- 3,3,3-(2,4,6-Trioxo-1,3,5-triazinane-1,3,5-triyl)tripropanenitrile (CAS 2904-28-1)
- 9,10,10-Trioxo-9h-10lambda6-thioxanthene-3-carboxamide (CAS 51762-93-7)
- 3,5,10-Trioxo-2,3,5,10-tetrahydrobenzo[g]isoquinolin-9-yl acetate (CAS 135735-66-9)
Recommended Standards
- 1-Boc-piperidine-2-boronic Acid Pinacol Ester (CAS 2071192-58-8)
- 2-(Azepan-1-yl)-N-(4-bromophenyl)acetamide (CAS 89473-76-7)
- 1-[(5-bromothiophen-2-yl)sulfonyl]piperazine (CAS 725688-07-3)
- 2-Bromo-N-((1-methylpiperidin-4-yl)methyl)benzamide (CAS 954074-39-6)
- 2-Chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine (CAS 1310404-27-3)
- 4-Iodo-2,2'-bipyridine (CAS 160539-03-7)
- 2-((2,5-Dimethoxyphenyl)carbamoyl)benzoic acid (CAS 19368-27-5)
- 2-(4-(((5-Fluorothiophen-2-yl)methyl)amino)-1H-pyrazol-1-yl)acetic acid hydrochloride (CAS 1856041-26-3)
- (Benzylsulfamoyl)({[3-(trifluoromethyl)phenyl]methyl})amine (CAS 337924-16-0)
- 4-Chloro-3-(cyanomethyl)-6-(difluoromethyl)picolinonitrile (CAS 1804665-98-2)
- Benzylpenicillin Impurity 34 (CAS 56609-07-5)
- 4-[4-(1-hydroxyethyl)-2-methoxy-5-nitrophenoxy]butyric acid (CAS 175281-76-2)
- 3,6-Dihydro-2H-pyran-4-carboxylic acid (CAS 99338-32-6)
- Exenatide (CAS 141758-74-9)
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