4-[(3,4-Dichlorophenyl)methoxy]-N'-[(1E)-phenylmethylidene]benzohydrazide CAS 320423-55-0
| CAS No. | 320423-55-0 |
| Molecular Formula | C21H16Cl2N2O2 |
| Molecular Weight | 399.27 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-[(3,4-Dichlorophenyl)methoxy]-N'-[(1E)-phenylmethylidene]benzohydrazide (CAS 320423-55-0), molecular formula C21H16Cl2N2O2 and molecular weight 399.27 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 4-[(3,4-Dichlorophenyl)methoxy]-N'-[(1E)-phenylmethylidene]benzohydrazide (C21H16Cl2N2O2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 4-[(3,4-Dichlorophenyl)methoxy]-N'-[(1E)-phenylmethylidene]benzohydrazide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C21H16Cl2N2O2 |
| Molecular Weight | 399.27 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
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Recommended Standards
- 2-Oxopropyl (Z)-N-(2-chloro-6-fluorobenzoyl)-N'-(4-chlorophenyl)carbamimidothioate (CAS 286841-40-5)
- 6-Chloro-1-((2-chlorobenzyl)oxy)-2-(4-methoxyphenyl)-1H-benzo[d]imidazole (CAS 329234-77-7)
- 2-[5,7-Bis(trifluoromethyl)-1,8-naphthyridin-2-yl]-2-(4-fluorophenyl)acetonitrile (CAS 478043-28-6)
- 6-Chloro-1-((3-chlorobenzyl)oxy)-2-(4-methoxyphenyl)-1H-benzo[d]imidazole (CAS 329234-83-5)
- 1-Benzyl-4-[(6,7-dimethoxy-1-oxoindan-2-yl)methyl]piperidine (CAS 736104-42-0)
- 4-(2-(Allylthio)benzo[4,5]thieno[3,2-d]pyrimidin-4-yl)morpholine (CAS 478029-86-6)
- 6-(2-Chlorophenyl)pyridin-3-amine (CAS 1119089-76-7)
- (5S)-5-Aminopiperidin-2-one dihydrochloride (CAS 1003021-05-3)
- Methyl 5'H-spiro[piperidine-4,4'-pyrrolo[1,2-a]quinoxaline]-7'-carboxylate hydrochloride (CAS 1242268-06-9)
- 1-Octene-1,1-d (CAS 54439-94-0)
- 1-(4-Nitrophenyl)-3-phenylpropane-1,3-dione (CAS 5400-95-3)
- 4-(4-Bromo-1h-pyrazol-1-yl)-2-(isopropylamino)butanamide (CAS 1340433-43-3)
- Dynarrestin (CAS 2222768-84-3)
- Peptide Impurity 04 (CAS 2913424-91-4)
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