3-(2-Chlorophenyl)-5-[(E)-2-[(4-chlorophenyl)amino]ethenyl]-1,2-oxazole-4-carbonitrile CAS 320424-88-2
| CAS No. | 320424-88-2 |
| Molecular Formula | C18H11Cl2N3O |
| Molecular Weight | 356.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
3-(2-Chlorophenyl)-5-[(E)-2-[(4-chlorophenyl)amino]ethenyl]-1,2-oxazole-4-carbonitrile (CAS 320424-88-2) is a high-purity analytical reference standard with the molecular formula C18H11Cl2N3O and a molecular weight of 356.21 g/mol.
3-(2-Chlorophenyl)-5-[(E)-2-[(4-chlorophenyl)amino]ethenyl]-1,2-oxazole-4-carbonitrile (C18H11Cl2N3O) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), 3-(2-Chlorophenyl)-5-[(E)-2-[(4-chlorophenyl)amino]ethenyl]-1,2-oxazole-4-carbonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H11Cl2N3O |
| Molecular Weight | 356.21 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Chlorophenyl Standards
- (E)-3-(2-chlorophenyl)-5-(2-((2-chlorophenyl)amino)vinyl)isoxazole-4-carbonitrile (CAS 320415-81-4)
- 3-(2-Chlorophenyl)-5-[(E)-2-[(3-chlorophenyl)amino]ethenyl]-1,2-oxazole-4-carbonitrile (CAS 320415-79-0)
- (E)-[1-(4-Chlorophenyl)-2-[(4-chlorophenyl)methanesulfinyl]ethylidene](methoxy)amine (CAS 320422-57-9)
- 2-(4-Chlorophenyl)-N-(2-((4-chlorophenyl)sulfinyl)ethyl)acetamide (CAS 477710-09-1)
- N-(4-Chlorophenyl)-3-[(4-chlorophenyl)sulfanyl]-2-hydroxy-2-methylpropanamide (CAS 339275-82-0)
- 2-(3-Chlorophenyl)-4-(thiophen-2-yl)-2,3-dihydrobenzo[b][1,4]thiazepine (CAS 866136-88-1)
- (2E)-3-{4-[(3-chlorophenyl)methoxy]phenyl}-N-cyclopentylprop-2-enamide (CAS 477871-22-0)
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Recommended Standards
- 4-Bromo-1'-methyl-3-phenyl-5H-spiro[furan-2,3'-indolin]-2'-one (CAS 882041-53-4)
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- 4-Chloro-2-(3-chlorophenyl)-6-(4-methoxyphenyl)pyrimidine-5-carbonitrile (CAS 477873-08-8)
- 2-(4-Bromophenyl)-6,8-dimethylquinoline-4-carboxylic acid (CAS 342017-99-6)
- (R)-3-((2-Methoxyphenyl)thio)pyrrolidine hydrochloride (CAS 1417789-77-5)
- 3-Amino-4-chloro-n-methoxy-n-methylbenzenesulfonamide (CAS 1156152-31-6)
- 5-Cyanoimidazo[1,2-a]pyridine-3-carboxylic acid (CAS 1936289-25-6)
- 1-[4-(9H-Carbazol-9-yl)phenyl]ethanone (CAS 142116-85-6)
- 3-Diphenylphosphanyl-N,N-dimethyl-propan-1-amine (CAS 961-04-6)
- Methyl (s)-3-amino-3-(3,5-dimethylphenyl)propanoate (CAS 1213443-23-2)
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- 7-Bromo-4-chloroquinazoline (CAS 573675-55-5)
- Methyl 2-(6,6-dimethylmorpholin-2-yl)acetate (CAS 2091554-58-2)
- D-Thr5-Tirzepatide (CAS CATO-CPTD788926)
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