1-Boc-4-isocyanatopiperidine CAS 320581-97-3
| CAS No. | 320581-97-3 |
| Molecular Formula | C11H18N2O3 |
| Molecular Weight | 226.27 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 1-Boc-4-isocyanatopiperidine (C11H18N2O3) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
1-Boc-4-isocyanatopiperidine (CAS 320581-97-3), molecular formula C11H18N2O3 and molecular weight 226.27 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1-Boc-4-isocyanatopiperidine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H18N2O3 |
| Molecular Weight | 226.27 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 2 |
Recommended Standards
- 1-[4-(2-methoxyphenyl)phenyl]ethan-1-one (CAS 52807-17-7)
- 1-Cyclobutyl-6-methoxy-1H-indole-3-carbonitrile (CAS 944563-38-6)
- 1-[(2,5-Difluorophenyl)methyl]piperidin-4-amine (CAS 380424-83-9)
- 1-ethyl-4-oxo-1,4-dihydrocinnoline-3-carboxylic acid (CAS 719-58-4)
- (R)-2-Acetamido-N-((2R,3R,4R,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-2-(((1S,2R,3R,4S,5S,6R)-2,3,4,5,6-pentahydroxycyclohexyl)oxy)tetrahydro-2H-pyran-3-yl)-3-mercaptopropanamide (CAS 192126-76-4)
- tert-Butyl 2-bromo-7-azaspiro[3.5]nonane-7-carboxylate (CAS 1225276-07-2)
- 6-(4-Fluorophenyl)-2-(2-methylbenzyl)pyridazin-3(2H)-one (CAS 941883-24-5)
- Methyl 4,5-dihydroxy-2-nitrobenzoate (CAS 773874-74-1)
- tert-Butyl 2-(Aminomethyl)-4-methylbenzylcarbamate (CAS 862205-35-4)
- Etoricoxib Impurity 89 (CAS CATO-C4X-108089)
- 4’-Methyl-[2,2’-bipyridine]-4-carbaldehyde (CAS 104704-09-8)
- (Z)-5-(furan-2-ylmethylene)-2-thioxothiazolidin-4-one (CAS 521972-99-6)
- (2R,3S,4R)-4-((tert-Butyldiphenylsilyl)oxy)-2-(((tert-butyldiphenylsilyl)oxy)methyl)-3,4-dihydro-2H-pyran-3-yl acetate (CAS 342029-19-0)
- Neuropeptide EI (human, mouse, rat) (CAS 125934-45-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com