Tranilast Impurity 8 CAS 320777-16-0
| CAS No. | 320777-16-0 |
| Molecular Formula | C14H10Cl3NO2 |
| Molecular Weight | 330.59 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Tranilast Impurity 8 (CAS 320777-16-0) is a certified pharmaceutical impurity reference standard with the molecular formula C14H10Cl3NO2 and a molecular weight of 330.59 g/mol.
Based on its molecular formula C14H10Cl3NO2, Tranilast Impurity 8 contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 330.59 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), Tranilast Impurity 8 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H10Cl3NO2 |
| Molecular Weight | 330.59 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Tranilast Standards
- Tranilast Impurity 1 (CAS 70806-55-2)
- Tranilast Impurity 2 (CAS 91920-58-0)
- Tranilast (CAS 53902-12-8)
- Tranilast Impurity 13 (CAS CATO-C4X-252913)
- Tranilast impurity 5 (CAS 697235-52-2)
- Tranilast Impurity 7 (CAS 93755-77-2)
- Tranilast Impurity 12 (CAS CATO-C4X-252912)
- Tranilast Impurity 11 (CAS CATO-C4X-252911)
Recommended Standards
- Dotinurad Impurity 181 (CAS 425666-79-1)
- tert-Butyl 4-bromo-5-chloro-1H-indole-1-carboxylate (CAS 1191028-42-8)
- 5-beta-Cholane (CAS 80373-86-0)
- N-Boc-3-bromo-6-chloroindole (CAS 1246471-36-2)
- Tafluprost Impurity 4 (CAS CATO-C4X-21634)
- Linagliptin impurity 98 (CAS CATO-C4X-110198)
- Acipimox Impurity 6 (CAS 32046-09-6)
- N-(2-Methoxybenzyl)-3-pentanamine hydrobromide (CAS 1609407-77-3)
- Perfluorophenyl 2-(acetylthio)acetate (CAS 129815-48-1)
- 3-(tert-Butyl)-4-[(4-chlorophenyl)sulfonyl]-6-methyl-3,4-dihydro-2H-1,4-benzoxazine (CAS 478048-81-6)
- 3-Cyclopropyl-2-(thietan-3-ylamino)propan-1-ol (CAS 1855651-86-3)
- Ethyl 3-Chloropyridazine-4-carboxylate (CAS 1445-54-1)
- 4-Chloro-2-methylfuro[2,3-d]pyrimidine (CAS 1782638-06-5)
- Xenopsin-Related Peptide 2 (XP-2) (H-9340.0005) (CAS 117442-29-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com