4-(2-Fluorophenyl)phenol CAS 321-62-0
| CAS No. | 321-62-0 |
| Molecular Formula | C12H9FO |
| Molecular Weight | 188.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-(2-Fluorophenyl)phenol.
CATO supplies 4-(2-Fluorophenyl)phenol (CAS 321-62-0), a certified reference material (molecular formula C12H9FO, MW 188.20 g/mol) for analytical method development and quality control.
The molecular framework of 4-(2-Fluorophenyl)phenol (C12H9FO) is characterized by a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H9FO |
| Molecular Weight | 188.20 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
Related Fluorophenyl Standards
- 3-(4-Fluorophenyl)phenol (CAS 10540-41-7)
- 4-(3-Fluorophenyl)pyridin-2-amine (CAS 1159815-31-2)
- 4-(2-Fluorophenyl)pyridin-2-amine (CAS 1159817-35-2)
- 6-(4-Fluorophenyl)pyridin-2-amine (CAS 1159819-35-8)
- 6-(3-Fluorophenyl)-3-pyridinamine (CAS 1214327-17-9)
- 3-(4-Fluorophenyl)pyridin-2-amine (CAS 1214333-67-1)
- 2-(2-Fluorophenyl)pyridin-3-amine (CAS 1214351-77-5)
- 3-(4-Fluorophenyl)pyridin-4-amine (CAS 1214353-80-6)
Recommended Standards
- 3-Methoxybenzenesulfonic acid (CAS 34256-01-4)
- 4-(3-Fluorophenyl)-2-methylpyrimidine (CAS 85979-50-6)
- 3-fluoroimidazo[1,2-a]pyridine-2-carboxylic acid (CAS 898156-12-2)
- 4-(3-Fluorophenyl)phenol (CAS 64465-61-8)
- n,n-Dimethyl-4-(piperidin-2-yl)aniline (CAS 383127-98-8)
- 2-(3-Acetylphenyl)hexahydro-1H-isoindole-1,3(2H)-dione (CAS 339021-77-1)
- (E)-{[2-(2-{4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl}ethoxy)phenyl]methylidene}[(4-chlorophenyl)methoxy]amine (CAS 338409-03-3)
- 6-Benzyl-2-(cyclohexanecarboxamido)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxamide hydrochloride (CAS 1329866-42-3)
- 111507-77-8 7-Hydroxyfuro[4,3,2-de]chromen-4(2H)-one 8805AC C10H6O4 (CAS 111507-77-8)
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