5-Fluoroisatoic anhydride 5-fluoroisatonic anhydride 6-fluoroisatoic anhydride 6-fluoro isatin anhydride 6-Fluoro-1H-benzo[d][1,3]oxazine-2,4-dione 6-Fluoro-2H-3,1-benzoxazine-2,4(1H)-dione 321-69-7 CAS 321-69-7

Purity 97%+In StockPharmaceutical Standards
CAS No.321-69-7
Molecular FormulaC8H10FNO3
Molecular Weight187.17 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

5-Fluoroisatoic anhydride 5-fluoroisatonic anhydride 6-fluoroisatoic anhydride 6-fluoro isatin anhydride 6-Fluoro-1H-benzo[d][1,3]oxazine-2,4-dione 6-Fluoro-2H-3,1-benzoxazine-2,4(1H)-dione 321-69-7 CAS 321-69-7 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-Fluoroisatoic anhydride 5-fluoroisatonic anhydride 6-fluoroisatoic anhydride 6-fluoro isatin anhydride 6-Fluoro-1H-benzo[d][1,3]oxazine-2,4-dione 6-Fluoro-2H-3,1-benzoxazine-2,4(1H)-dione 321-69-7.

5-Fluoroisatoic anhydride 5-fluoroisatonic anhydride 6-fluoroisatoic anhydride 6-fluoro isatin anhydride 6-Fluoro-1H-benzo[d][1,3]oxazine-2,4-dione 6-Fluoro-2H-3,1-benzoxazine-2,4(1H)-dione 321-69-7 (CAS 321-69-7), molecular formula C8H10FNO3 and molecular weight 187.17 g/mol, is a CATO reference standard with documented purity and traceability.

5-Fluoroisatoic anhydride 5-fluoroisatonic anhydride 6-fluoroisatoic anhydride 6-fluoro isatin anhydride 6-Fluoro-1H-benzo[d][1,3]oxazine-2,4-dione 6-Fluoro-2H-3,1-benzoxazine-2,4(1H)-dione 321-69-7 (C8H10FNO3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 5-Fluoroisatoic anhydride 5-fluoroisatonic anhydride 6-fluoroisatoic anhydride 6-fluoro isatin anhydride 6-Fluoro-1H-benzo[d][1,3]oxazine-2,4-dione 6-Fluoro-2H-3,1-benzoxazine-2,4(1H)-dione 321-69-7 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC8H10FNO3
Molecular Weight187.17 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, ethanol, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)4.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1957
Halogen ContentF-containing
Nitrogen Atoms1

Recommended Standards

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