3-(Trifluoromethoxy)benzohydrazide CAS 321195-88-4
| CAS No. | 321195-88-4 |
| Molecular Formula | C8H7F3N2O2 |
| Molecular Weight | 220.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 3-(Trifluoromethoxy)benzohydrazide is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 3-(Trifluoromethoxy)benzohydrazide (CAS 321195-88-4), a certified reference material (molecular formula C8H7F3N2O2, MW 220.15 g/mol) for analytical method development and quality control.
3-(Trifluoromethoxy)benzohydrazide (C8H7F3N2O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H7F3N2O2 |
| Molecular Weight | 220.15 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Trifluoromethoxy Standards
- 5-Methyl-2-(trifluoromethoxy)benzoic acid (CAS 1261573-49-2)
- 4-Methyl-2-(trifluoromethoxy)benzoic acid (CAS 1261747-62-9)
- 3-methyl-4-(trifluoromethoxy)benzoic acid (CAS 1261753-62-1)
- 2-Methyl-3-(trifluoromethoxy)benzoic acid (CAS 1261764-39-9)
- 4-[(trifluoromethoxy)methyl]benzoic acid (CAS 1262413-29-5)
- Methyl 2-(Trifluoromethoxy)benzoate (CAS 148437-99-4)
- Methyl 3-(trifluoromethoxy)benzoate (CAS 148438-00-0)
- 4-(Trifluoromethoxy)benzohydrazide (CAS 175277-18-6)
Recommended Standards
- 3-(Methylamino)-5-(trifluoromethyl)-pyridine-2-carboxylic acid (CAS 1987078-32-9)
- 3-(Trifluoromethoxy)phenylacetic Acid (CAS 203302-97-0)
- 3-(Hydroxymethyl)-5-(trifluoromethoxy)benzaldehyde (CAS 2828405-70-3)
- 3,3,3-Trifluoro-2-hydroxy-2-phenylpropanoic acid (CAS 55519-22-7)
- 3-Fluorophenoxathiine (CAS 205187-77-5)
- 3-(4-Fluorobenzyl)-1-methylpiperidin-4-amine hydrochloride (CAS 1822842-15-8)
- Diisobutyl Cyclohexane-1,2-Dicarboxylate (CAS 70969-58-3)
- 4-methoxyquinoline-2-carboxylic acid (CAS 15733-83-2)
- (6-Dimethylaminomethyl-2-piperidin-2-yl-pyrimidin-4-yl)-methyl-amine trihydrochloride (CAS 1361115-89-0)
- (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(2,3,4-trimethoxyphenyl)propanoic acid (CAS 381222-52-2)
- N-(3,4-dimethylphenyl)-2-((4-fluorophenyl)sulfonamido)-4-methylpentanamide (CAS 317378-00-0)
- 2-(3-Cyclopropyl-6-(1-ethyl-1h-pyrazol-4-yl)-4-(trifluoromethyl)-1h-pyrazolo[3,4-b]pyridin-1-yl)acetic acid (CAS 1006477-52-6)
- Tert-butyl (1-(azetidin-3-yl)ethyl)carbamate hydrochloride (CAS 1379363-25-3)
- Peptide 435 (CAS CATO-CPTD788435)
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