3,4-Difluoro-DL-phenylalanine CAS 32133-36-1
| CAS No. | 32133-36-1 |
| Molecular Formula | C9H9F2NO2 |
| Molecular Weight | 201.17 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 3,4-Difluoro-DL-phenylalanine is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
3,4-Difluoro-DL-phenylalanine (CAS 32133-36-1) is a high-purity analytical reference standard with the molecular formula C9H9F2NO2 and a molecular weight of 201.17 g/mol.
3,4-Difluoro-DL-phenylalanine (C9H9F2NO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H9F2NO2 |
| Molecular Weight | 201.17 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1966 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Difluoro Standards
- Methyl 5,5-difluoro-1,4,5,6-tetrahydrocyclopenta[b]pyrrole-2-carboxylate (CAS 1041430-65-2)
- Ethyl 2,2-difluoro-2-(pyridin-4-yl)acetate (CAS 1255305-76-0)
- 3,4-difluoro-N-methoxy-N-methylbenzamide (CAS 188345-25-7)
- [(2,2-Difluoro-2H-1,3-benzodioxol-5-yl)methyl](methyl)amine (CAS 381236-72-2)
- 2,3-Difluoro-L-phenylalanine (CAS 266360-42-3)
- 2,3-Difluoro-N-methoxy-N-methylbenzamide (CAS 680610-58-6)
- 2,4-Difluoro-DL-phenylalanine (CAS 32133-35-0)
- 2,4-Difluoro-L-phenylalanine (CAS 31105-93-8)
Recommended Standards
- 2-Amino-3-(2,5-difluorophenyl)propanoic acid (CAS 32133-38-3)
- 3,4-Difluoro-L-phenylalanine (CAS 31105-90-5)
- 2-Amino-3-(2,3-difluorophenyl)propanoic acid (CAS 236754-62-4)
- 3,5-Difluoro-DL-phenylalanine (CAS 32133-37-2)
- (1R,2S)-2-morpholino-1-phenylpropan-1-ol (CAS 335331-71-0)
- 9-Hydroxy-10-oxo-cis-12-octadecenoic Acid (CAS 26369-27-7)
- 1-Benzyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2,5-dihydro-1H-pyrrole (CAS 439813-70-4)
- Ikarugamycin (CAS 36531-78-9)
- Bis(2,3-dibromopropyl) Phosphate (CAS 5412-25-9)
- 3,5-Dibromobenzohydrazide (CAS 610258-34-9)
- (2-(4-Nitrophenyl)-2-oxoethyl)triphenylphosphonium bromide (CAS 17730-93-7)
- N-(Acridin-9-yl)morpholin-4-amine (CAS 28846-41-5)
- 4-Bromo-2-chlorobenzhydrazide (CAS 206559-39-9)
- Semaglutide impurity 237 (CAS CATO-C4X-2226237)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com