4-(4-(4-Fluorophenyl)thiazol-2-yl)benzoic acid CAS 321429-96-3
| CAS No. | 321429-96-3 |
| Molecular Formula | C16H10FNO2S |
| Molecular Weight | 299.32 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4-(4-(4-Fluorophenyl)thiazol-2-yl)benzoic acid is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 4-(4-(4-Fluorophenyl)thiazol-2-yl)benzoic acid (CAS 321429-96-3), a certified reference material (molecular formula C16H10FNO2S, MW 299.32 g/mol) for analytical method development and quality control.
The molecular framework of 4-(4-(4-Fluorophenyl)thiazol-2-yl)benzoic acid (C16H10FNO2S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4-(4-(4-Fluorophenyl)thiazol-2-yl)benzoic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H10FNO2S |
| Molecular Weight | 299.32 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Fluorophenyl Standards
- N-((1-(3-Fluorophenyl)-1H-tetrazol-5-yl)methyl)propane-1-sulfonamide (CAS 921060-78-8)
- N-((1-(4-Fluorophenyl)-1H-tetrazol-5-yl)methyl)propane-1-sulfonamide (CAS 920469-48-3)
- N-(5-(4-Fluorophenyl)-1,3,4-thiadiazol-2-yl)benzamide (CAS 391226-17-8)
- 5-(4-Fluorophenyl)-4-((pyridin-3-ylmethylene)amino)-4H-1,2,4-triazole-3-thiol (CAS 674788-72-8)
- 5-[(2-Fluorophenyl)methyl]-2-[(1H-1,2,4-triazol-1-yl)methyl]pyrimidine-4,6-diamine (CAS 338965-24-5)
- methyl 1-(4-fluorophenyl)-3,6-dimethyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylate (CAS 1011370-87-8)
- 1-(2-Fluorophenyl)-6-isopropyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid (CAS 1018127-29-1)
- 1-(4-fluorophenyl)-6-isopropyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid (CAS 1018127-53-1)
Recommended Standards
- 4-(2-Methyl-4,5,6,7-tetrahydrobenzofuran-3-carboxamido)benzoic acid (CAS 335211-75-1)
- 4-(4-Tert-butylphenoxy)-3-nitrobenzaldehyde (CAS 726151-45-7)
- 4-(2-((Cyclohexanecarbonyl)glycyl)hydrazinyl)-4-oxobutanoic acid (CAS 817191-55-2)
- 4-(Furan-2-carbonyl)-N-phenylpiperazine-1-carboxamide (CAS 870674-39-8)
- 2-((3-Oxo-2-(3,4,5-trimethoxybenzylidene)-2,3-dihydrobenzofuran-6-yl)oxy)acetic acid (CAS 859662-11-6)
- 1-(2-Fluorophenyl)-2-(trifluoromethoxy)ethan-1-amine (CAS 1334147-38-4)
- 5-Bromo-2-(cyclohexyloxy)phenol (CAS 1243367-56-7)
- 4-Phenyl-1,2,5-thiadiazol-3-amine (CAS 33710-58-6)
- 1,3-Bis(hydroxymethyl)-1,3,5-triazinan-2-one (CAS 19708-68-0)
- 1-(1-(Tert-butoxycarbonyl)-1,2,3,4-tetrahydroquinolin-6-yl)cyclohexane-1-carboxylic acid (CAS 1903098-01-0)
- 2-Isobutyloxazole-4-carboxylic acid (CAS 1248373-18-3)
- 4-Bromo-N-(4-fluoro-3-methylphenyl)-Benzenesulfonamide (CAS 1485880-01-0)
- Chola-3,5-dien-24-oic Acid, Methyl Ester (CAS 1172-10-7)
- Neuropeptide Y (3-36) (porcine) trifluoroacetate salt (CAS 143863-88-1)
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