4-Methyl-2-(pyridin-3-yl)-N-[3-(trifluoromethyl)phenyl]-1,3-thiazole-5-carboxamide CAS 321430-09-5
| CAS No. | 321430-09-5 |
| Molecular Formula | C17H12F3N3OS |
| Molecular Weight | 363.36 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4-Methyl-2-(pyridin-3-yl)-N-[3-(trifluoromethyl)phenyl]-1,3-thiazole-5-carboxamide is closely related to a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
4-Methyl-2-(pyridin-3-yl)-N-[3-(trifluoromethyl)phenyl]-1,3-thiazole-5-carboxamide (CAS 321430-09-5) is a high-purity analytical reference standard with the molecular formula C17H12F3N3OS and a molecular weight of 363.36 g/mol.
Structurally, 4-Methyl-2-(pyridin-3-yl)-N-[3-(trifluoromethyl)phenyl]-1,3-thiazole-5-carboxamide (C17H12F3N3OS) contains a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 12.0, corresponding to approximately 12 ring(s) or double-bond equivalent(s). With a molecular weight of 363.36 g/mol, it falls into the moderately-high-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-Methyl-2-(pyridin-3-yl)-N-[3-(trifluoromethyl)phenyl]-1,3-thiazole-5-carboxamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C17H12F3N3OS |
| Molecular Weight | 363.36 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Methyl Standards
- 4-Methyl-2-(pyridin-2-yl)-N-(3-(trifluoromethyl)phenyl)thiazole-5-carboxamide (CAS 400079-02-9)
- 4-Methyl-2-(pyridin-3-yl)-N-(4-(trifluoromethyl)phenyl)thiazole-5-carboxamide (CAS 321430-10-8)
- 4-Methyl-2-(pyridin-4-yl)-N-(3-(trifluoromethyl)phenyl)thiazole-5-carboxamide (CAS 338396-93-3)
- N-((1-(Pyridin-2-yl)piperidin-4-yl)methyl)-3-(trifluoromethyl)benzamide (CAS 1234813-12-7)
- 2,6-Bis(pyridin-4-ylethynyl)-4-(trifluoromethyl)aniline (CAS 1453188-67-4)
- 2-(((Pyridin-2-ylmethyl)(thiazol-2-ylmethyl)amino)methyl)quinolin-8-ol (CAS 648896-30-4)
- N-(Pyridin-3-ylmethyl)-2-(6-(p-tolyl)imidazo[2,1-b]thiazol-3-yl)acetamide (CAS 897463-14-8)
- 7-(Pyridin-4-yl)-9-(trifluoromethyl)pyrido[3',2':4,5]thieno[3,2-d]pyrimidine-2,4(1H,3H)-dione (CAS 625376-68-3)
Recommended Standards
- 5-({[(9H-fluoren-9-ylmethoxy)carbonyl]amino}methyl)furan-2-carboxylic acid (CAS 503469-51-0)
- 4-[(4-Methoxyphenyl)sulfanyl]-2-(pyridin-2-yl)-6-(trifluoromethyl)pyrimidine (CAS 338418-07-8)
- 5-Methoxy-2-(pyridin-2-yl)-4-{[3-(trifluoromethyl)phenyl]sulfanyl}pyrimidine (CAS 321432-99-9)
- 4-(Furan-2-carbonyl)-3-(4-methoxyphenyl)-2,3,4,5-tetrahydro-1,4-benzoxazepin-5-one (CAS 866134-18-1)
- 1-Hydroxyindolin-2-one (CAS 18108-55-9)
- 3-(4-Nitrophenyl)-6,7-diphenyl-2H-oxazolo[3,2-a][1,3,5]triazine-2,4(3H)-dione (CAS 35629-69-7)
- 2-Naphthalenecarboxylicacid,6-(4-carboxyphenoxy)- (CAS 124396-97-0)
- 5-(((4-Methoxyphenyl)thio)methyl)-1H-imidazole (CAS 40224-94-0)
- 3-Methyl-1-(4-methylbenzyl)-6-phenyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid (CAS 1011397-32-2)
- N-phenyl-1H-1,2,4-triazol-5-amine (CAS 2433-53-6)
- Moxifloxacin Impurity 52 (CAS CATO-C4X-107452)
- 17103-70-7 4-(3,5-Dimethoxyphenyl)-4-oxobutanoic acid DTXSID70567079 (CAS 17103-70-7)
- (R,R)-Formoterol Impurity 97 (CAS CATO-C4X-152552)
- (Glu9)-Exenatide (2-39) trifluoroacetate salt (CAS 196109-34-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com