N-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-3-oxobutanamide CAS 321430-23-3
| CAS No. | 321430-23-3 |
| Molecular Formula | C10H8ClF3N2O2 |
| Molecular Weight | 280.63 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including N-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-3-oxobutanamide.
CATO supplies N-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-3-oxobutanamide (CAS 321430-23-3), a certified reference material (molecular formula C10H8ClF3N2O2, MW 280.63 g/mol) for analytical method development and quality control.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, N-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-3-oxobutanamide is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 280.63 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), N-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-3-oxobutanamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H8ClF3N2O2 |
| Molecular Weight | 280.63 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related N Standards
- Methyl 3-chloro-2-oxo-3-(3-(trifluoromethyl)phenyl)propanoate (CAS 135026-70-9)
- Ethyl 2-(4-chloro-2-(trifluoromethyl)phenyl)-2-oxoacetate (CAS 1417508-25-8)
- 4-(4-Chloro-3-(trifluoromethyl)phenyl)-4-oxobutanoic acid (CAS 75381-63-4)
- 1-(3-Chloro-5-(pentafluoro-λ6-sulfanyl)phenyl)ethan-1-one (CAS 1180486-96-7)
- 1-Chloro-2-trifluoromethyl-4-trifluoromethylsulfanyl-benzene (CAS 1208079-27-9)
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Recommended Standards
- Ethyl N-[(1E)-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methylidene]carbamate (CAS 400088-16-6)
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