1,1-Bis(4-chlorophenyl)-2-((4-fluorobenzyl)amino)ethanol CAS 321432-79-5
| CAS No. | 321432-79-5 |
| Molecular Formula | C21H18Cl2FNO |
| Molecular Weight | 390.28 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 1,1-Bis(4-chlorophenyl)-2-((4-fluorobenzyl)amino)ethanol (C21H18Cl2FNO) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO supplies 1,1-Bis(4-chlorophenyl)-2-((4-fluorobenzyl)amino)ethanol (CAS 321432-79-5), a certified reference material (molecular formula C21H18Cl2FNO, MW 390.28 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1,1-Bis(4-chlorophenyl)-2-((4-fluorobenzyl)amino)ethanol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C21H18Cl2FNO |
| Molecular Weight | 390.28 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Bis Standards
- 1,1-Bis(4-chlorophenyl)-2-((2-fluorobenzyl)amino)ethan-1-ol (CAS 321432-80-8)
- 2-(4-Chlorophenyl)-2-{6-[(4-chlorophenyl)sulfanyl]pyridazin-3-yl}acetamide (CAS 303997-46-8)
- (4Z)-1-(4-Chlorophenyl)-4-({[(4-chlorophenyl)methyl]amino}methylidene)-3-ethoxy-4,5-dihydro-1H-pyrazol-5-one (CAS 338751-22-7)
- N-[(2-Chlorophenyl)methyl]-6-{[(4-chlorophenyl)sulfanyl]methyl}-2-methylpyrimidin-4-amine (CAS 338960-32-0)
- 1-(3-Chlorophenyl)-3-(m-tolyl)-2-(trichloromethyl)imidazolidine (CAS 61545-20-8)
- 1-(3-Chlorophenyl)-3-(p-tolyl)-2-(trichloromethyl)imidazolidine (CAS 61545-11-7)
- 1-(4-Chlorophenyl)-3-(p-tolyl)-2-(trichloromethyl)imidazolidine (CAS 61545-18-4)
- 2-((3-(2-Chlorophenyl)-1,2,4-thiadiazol-5-yl)thio)-N-(3,5-dimethylphenyl)acetamide (CAS 864919-11-9)
Recommended Standards
- 2-((2,4-Dichlorobenzyl)amino)-1-(4-fluorophenyl)-1-phenylethan-1-ol (CAS 338771-51-0)
- (2Z)-1-[5,6-Dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl]-4-(2,4,5-trifluorophenyl)-2-buten-1-one (CAS 1803026-54-1)
- 2-((3,4-Dichlorobenzyl)amino)-1-(4-fluorophenyl)-1-phenylethan-1-ol (CAS 338771-53-2)
- (5-((3,5-Dichlorophenyl)sulfinyl)-4-isopropyl-1-methyl-1H-imidazol-2-yl)methyl carbamate (CAS 178980-08-0)
- 1-benzylpiperazine-2,6-dione (CAS 69370-99-6)
- 1-Allyl-3,5-bis(oxiran-2-ylmethyl)-1,3,5-triazinane-2,4,6-trione (CAS 69731-45-9)
- 2-Chloro-n-{2,4-dioxo-1,3-diazaspiro[4.5]decan-3-yl}acetamide (CAS 568574-78-7)
- N-(4-Bromo-3-chlorophenyl)formamide (CAS 77897-92-8)
- 3-(Furan-3-yl)-4-methylaniline (CAS 710351-88-5)
- 1-Chloro-4-(3-chloro-2-methylpropyl)benzene (CAS 861362-73-4)
- 3-(3,4-Difluorobenzenesulfonamido)benzoic acid (CAS 329268-45-3)
- N-Notroso Minocycline impurity 78 (CAS CATO-C4X-169978)
- 3-(5-Bromo-2-fluorophenyl)-2,2-dimethylpropan-1-ol (CAS 1489177-90-3)
- Anti-Inflammatory Peptide 3 (CAS 118850-73-0)
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