1-(4-chlorophenyl)-2-{[(3-methoxyphenyl)methyl]amino}-1-phenylethan-1-ol hydrochloride 12H-353S 321521-66-8 CAS 321521-66-8
| CAS No. | 321521-66-8 |
| Molecular Formula | C22H23ClNO2 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 1-(4-chlorophenyl)-2-{[(3-methoxyphenyl)methyl]amino}-1-phenylethan-1-ol hydrochloride 12H-353S 321521-66-8 is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
1-(4-chlorophenyl)-2-{[(3-methoxyphenyl)methyl]amino}-1-phenylethan-1-ol hydrochloride 12H-353S 321521-66-8 (CAS 321521-66-8), molecular formula C22H23ClNO2Cl and molecular weight 404.33 g/mol, is a CATO reference standard with documented purity and traceability.
1-(4-chlorophenyl)-2-{[(3-methoxyphenyl)methyl]amino}-1-phenylethan-1-ol hydrochloride 12H-353S 321521-66-8 (C22H23ClNO2Cl) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H23ClNO2 Cl |
| Molecular Weight | 404.33 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related chlorophenyl Standards
- 2-(2-Chlorophenyl)-2-(pyrrolidin-1-yl)acetamide (CAS 1000340-02-2)
- N-(2-Chlorophenyl)-5-methyl-1-phenyl-1H-1,2,4-triazole-3-carboxamide (CAS 1000572-01-9)
- N-(2-Chlorophenyl)-5-oxo-1-(p-tolyl)-2,5-dihydro-1H-1,2,4-triazole-3-carboxamide (CAS 1000573-94-3)
- Methyl 1-(2-chlorophenyl)-2,5-dihydro-5-oxo-1H-1,2,4-triazole-3-carboxylate (CAS 1000576-85-1)
- 1-(4-Chlorophenyl)-2,5-dihydro-5-oxo-1H-1,2,4-triazole-3-carboxylic acid phenylamide (CAS 1000577-01-4)
- Benzyl 1-(4-chlorophenyl)-2,5-dihydro-5-oxo-1H-1,2,4-triazole-3-carboxylate (CAS 1000577-09-2)
- 1-(2-Chlorophenyl)-5-oxo-N-phenyl-2,5-dihydro-1H-1,2,4-triazole-3-carboxamide (CAS 1000577-29-6)
- 2-(2-Chlorophenyl)-1-phenylethan-1-amine (CAS 1000615-44-0)
Recommended Standards
- [1,2,4]triazolo[1,5-a]pyrimidine (CAS 275-02-5)
- Ethyl 5-oxo-1-phenylpyrrolidine-3-carboxylate (CAS 91957-98-1)
- TERT-BUTYL ETHYL3-HYDROXYPROPYLCARBAMATE (CAS 182951-96-8)
- Plerixafor Impurity 30 6HCl (CAS CATO-C4X-113330)
- 2-Chloro-1-(3-(methylthio)phenyl)ethan-1-one (CAS 1352209-44-9)
- 2,4-Dichloro-N-(2-((2-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)amino)ethyl)amino)pyridin-3-yl)benzamide (CAS 338772-73-9)
- 2-[2-(4-Chloro-2-nitrophenyl)diazenyl]-3-oxo-N-phenylbutanamide (CAS 4106-76-7)
- Methyl 1-(cyclopropylmethyl)-1H-pyrazole-4-carboxylate (CAS 1823363-58-1)
- N5,1-Diethyl-1H-pyrazole-4,5-diamine (CAS 474649-93-9)
- Semaglutide impurity 237 (CAS CATO-C4X-2226237)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com