1-((2,4-Dichlorophenyl)sulfonyl)-4-(3,4-dimethoxyphenyl)-3-methyl-1H-pyrazole CAS 321526-11-8
| CAS No. | 321526-11-8 |
| Molecular Formula | C18H16Cl2N2O4S |
| Molecular Weight | 427.30 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1-((2,4-Dichlorophenyl)sulfonyl)-4-(3,4-dimethoxyphenyl)-3-methyl-1H-pyrazole (CAS 321526-11-8), molecular formula C18H16Cl2N2O4S and molecular weight 427.30 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 1-((2,4-Dichlorophenyl)sulfonyl)-4-(3,4-dimethoxyphenyl)-3-methyl-1H-pyrazole (C18H16Cl2N2O4S) is characterized by a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1-((2,4-Dichlorophenyl)sulfonyl)-4-(3,4-dimethoxyphenyl)-3-methyl-1H-pyrazole meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H16Cl2N2O4S |
| Molecular Weight | 427.30 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Dichlorophenyl Standards
- 1-((2,5-Dichlorophenyl)sulfonyl)-4-(2-hydroxyethyl)-5-methyl-2-phenyl-1,2-dihydro-3H-pyrazol-3-one (CAS 866040-23-5)
- 3-Benzyl-5-{4-[(2,4-dichlorophenyl)methoxy]phenyl}-2,3-dihydro-1,3,4-oxadiazol-2-one (CAS 866152-88-7)
- 2-((2-(3,4-Dichlorophenyl)-2-oxoethyl)thio)-3-ethyl-5,6-dimethylthieno[2,3-d]pyrimidin-4(3H)-one (CAS 585563-60-6)
- N-(3,5-dichlorophenyl)-3-(2-fluoro-4-nitrophenoxy)thiophene-2-carboxamide (CAS 303152-54-7)
- 1-(2,4-dichlorophenyl)-3-{5-[2-(trifluoromethoxy)phenyl]-2-furyl}prop-2-en-1-one (CAS 259196-59-3)
- N-((2,4-dichlorophenyl)sulfonyl)-N-(3-(trifluoromethyl)phenyl)glycine (CAS 337922-15-3)
- (2E)-1-{3-[(2,4-dichlorophenyl)methoxy]phenyl}-3-[(4-ethylphenyl)amino]prop-2-en-1-one (CAS 478046-59-2)
- (2,4-Dichlorophenyl)(1-methyl-5-(5-(phenoxymethyl)-1,3,4-oxadiazol-2-yl)-1H-pyrrol-3-yl)methanone (CAS 338418-65-8)
Recommended Standards
- 3-(Trifluoromethyl)phenyl 2-[3-(trifluoromethyl)phenoxy]pyridine-3-carboxylate (CAS 1795491-19-8)
- 2-Benzyl 1-(tert-butyl) 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrole-1,2-dicarboxylate (CAS 1233525-93-3)
- 2-((2-((2,4-Dichloro-5-(2-methoxyethoxy)phenyl)amino)-2-oxoethyl)sulfonyl)-N,N-dimethylacetamide (CAS 341965-04-6)
- Remimazolam Impurity 17 (CAS CATO-C4X-282317)
- 3-Hydroxy-5,7-dimethylindolin-2-one (CAS 1195186-48-1)
- Hetacillin potassium (CAS 5321-32-4)
- 6-Chloro-2-hydrazinyl-4-methylquinoline (CAS 21703-54-8)
- 3-(3,4-Dihydroisoquinolin-2(1H)-yl)butanoic acid (CAS 1153828-35-3)
- 6-Chloro-2-methyl-4-(piperazin-1-yl)quinoline (CAS 1146293-27-7)
- 5-Phenylbenzo[d]oxazole-2-thiol (CAS 17371-99-2)
- 3-Bromo-5-chloro-2-fluorophenol (CAS 1804897-55-9)
- 2-(4-Formylphenoxy)-N-(pyridin-2-yl)acetamide (CAS 329211-31-6)
- 1-(1-(4-Fluorobenzyl)-1H-pyrazol-4-yl)ethan-1-one (CAS 500367-17-9)
- Semaglutide impurity 66 (CAS CATO-C4X-222666)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com