6-[1-(4-Fluorophenyl)-1H-pyrazol-5-yl]-2-(3-methoxyphenyl)-4-methyl-2,3,4,5-tetrahydro-1,2,4-triazine-3,5-dione CAS 321538-37-8
| CAS No. | 321538-37-8 |
| Molecular Formula | C20H16FN5O3 |
| Molecular Weight | 393.37 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 6-[1-(4-Fluorophenyl)-1H-pyrazol-5-yl]-2-(3-methoxyphenyl)-4-methyl-2,3,4,5-tetrahydro-1,2,4-triazine-3,5-dione.
6-[1-(4-Fluorophenyl)-1H-pyrazol-5-yl]-2-(3-methoxyphenyl)-4-methyl-2,3,4,5-tetrahydro-1,2,4-triazine-3,5-dione (CAS 321538-37-8), molecular formula C20H16FN5O3 and molecular weight 393.37 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C20H16FN5O3, 6-[1-(4-Fluorophenyl)-1H-pyrazol-5-yl]-2-(3-methoxyphenyl)-4-methyl-2,3,4,5-tetrahydro-1,2,4-triazine-3,5-dione contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 393.37 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 6-[1-(4-Fluorophenyl)-1H-pyrazol-5-yl]-2-(3-methoxyphenyl)-4-methyl-2,3,4,5-tetrahydro-1,2,4-triazine-3,5-dione meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C20H16FN5O3 |
| Molecular Weight | 393.37 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 5 |
Related Fluorophenyl Standards
- (4-((4-Fluorophenyl)sulfonyl)piperazin-1-yl)(4-nitrophenyl)methanone (CAS 428504-82-9)
- 3-(4-{[(3-Fluorophenyl)sulfonyl]amino}phenoxy)-2-thiophenecarboxylic acid (CAS 882747-66-2)
- N-(4-fluorophenyl)-1,3-dimethyl-5-(3-(trifluoromethyl)phenoxy)-1H-pyrazole-4-carboxamide (CAS 303997-88-8)
- N-{3-[(2-fluorophenyl)thio]propyl}-3-(trifluoromethyl)benzenesulphonamide (CAS 648408-66-6)
- N-[(4-Fluorophenyl)methyl]-2-{4-oxo-7-phenyl-3H,4H-thieno[3,2-d]pyrimidin-3-yl}acetamide (CAS 1105206-96-9)
- N-(4-Fluorophenyl)-2-[2-oxo-5-(piperidine-1-sulfonyl)-1,2-dihydropyridin-1-yl]acetamide (CAS 1251631-02-3)
- 4-(4-(4-Fluorophenyl)-2-(4-(methylsulfonyl)phenyl)-1H-imidazol-5-yl)pyridine (CAS 152121-46-5)
- 4-(2-((4-Fluorophenyl)sulfonyl)acetyl)-2,6-dimethylphenyl dimethylcarbamate (CAS 339112-17-3)
Recommended Standards
- N-(4-Fluoro-2-methoxy-5-nitrophenyl)-4-(1-methyl-1H-indol-3-yl)pyrimidin-2-amine (CAS 1421372-94-2)
- tert-Butyl [Bis(4-methoxyphenyl)phosphinyloxy]carbamate (CAS 619333-95-8)
- Lasmiditan Impurity 35 (CAS CATO-C4X-247835)
- Levofloxacin Impurity 53 (CAS CATO-C4X-137153)
- (2E)-1-(2,4-Dimethoxyphenyl)-3-(3,4-dimethoxyphenyl)prop-2-en-1-one (CAS 100753-43-3)
- 3-(2-Carboxyphenyl)-1-phenyl-1h-pyrazole-4-carboxylic acid (CAS 6110-61-8)
- 2-Methoxy-1-(4-methoxyphenyl)ethanone (CAS 21160-26-9)
- 2-Amino-4,5-dimethylbenzonitrile (CAS 28568-03-8)
- Fenitrothion (CAS 122-14-5)
- Ethyl 2-imino-1-(2-methoxyethyl)-5-oxo-2,5-dihydro-1H-dipyrido[1,2-a:2',3'-d]pyrimidine-3-carboxylate (CAS 371209-38-0)
- 6-Bromo-N-(pentan-3-yl)pyridazin-4-amine (CAS 2060007-40-9)
- 1-Methoxy-3-((methylsulfonyl)methyl)benzene (CAS 25195-41-9)
- Thiol-C9-PEG5 (CAS 130727-42-3)
- 302798-54-5 (Leu31,Pro34)-Neuropeptide Y (13-36) (human, rat) MFCD00672463 (CAS 302798-54-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com