3-[(1R,2R)-2-(Hydroxymethyl)-1H,2H,3H-naphtho[2,1-b]pyran-1-yl]-3-methyl-1-[3-(trifluoromethyl)phenyl]thiourea CAS 321574-22-5

Purity 97%+In StockPharmaceutical Standards
CAS No.321574-22-5
Molecular FormulaC23H21F3N2O2S
Molecular Weight446.49 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

3-[(1R,2R)-2-(Hydroxymethyl)-1H,2H,3H-naphtho[2,1-b]pyran-1-yl]-3-methyl-1-[3-(trifluoromethyl)phenyl]thiourea CAS 321574-22-5 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 446.49 g/mol gives 3-[(1R,2R)-2-(Hydroxymethyl)-1H,2H,3H-naphtho[2,1-b]pyran-1-yl]-3-methyl-1-[3-(trifluoromethyl)phenyl]thiourea distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies 3-[(1R,2R)-2-(Hydroxymethyl)-1H,2H,3H-naphtho[2,1-b]pyran-1-yl]-3-methyl-1-[3-(trifluoromethyl)phenyl]thiourea (CAS 321574-22-5), a certified reference material (molecular formula C23H21F3N2O2S, MW 446.49 g/mol) for analytical method development and quality control.

Owing to a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution, 3-[(1R,2R)-2-(Hydroxymethyl)-1H,2H,3H-naphtho[2,1-b]pyran-1-yl]-3-methyl-1-[3-(trifluoromethyl)phenyl]thiourea is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 446.49 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.

CATO manufactures 3-[(1R,2R)-2-(Hydroxymethyl)-1H,2H,3H-naphtho[2,1-b]pyran-1-yl]-3-methyl-1-[3-(trifluoromethyl)phenyl]thiourea under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC23H21F3N2O2S
Molecular Weight446.49 g/mol
Purity97%+
StorageStore in a cool place (≤25°C), protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)13.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentF-containing
Nitrogen Atoms2
Sulfur Atoms1

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