3,4-Difluoro-N-(4-methylbenzyl)benzenesulfonamide CAS 321705-77-5
| CAS No. | 321705-77-5 |
| Molecular Formula | C14H13F2NO2S |
| Molecular Weight | 297.32 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 3,4-Difluoro-N-(4-methylbenzyl)benzenesulfonamide (CAS 321705-77-5), a certified reference material (molecular formula C14H13F2NO2S, MW 297.32 g/mol) for analytical method development and quality control.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution, 3,4-Difluoro-N-(4-methylbenzyl)benzenesulfonamide is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 297.32 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 3,4-Difluoro-N-(4-methylbenzyl)benzenesulfonamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H13F2NO2S |
| Molecular Weight | 297.32 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Difluoro Standards
- (S)-4,4-difluoro-N-(3-hydroxy-1-phenylpropyl)cyclohexane-1-carboxamide (CAS 376348-77-5)
- Ethyl (3,4-difluoro-2-((trimethylsilyl)ethynyl)phenyl)carbamate (CAS 1268052-96-5)
- Ethyl (2,4-difluoro-6-((trimethylsilyl)ethynyl)phenyl)carbamate (CAS 500139-00-4)
- 6,7-Difluoro-1-isopropyl-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (CAS 874482-59-4)
- 3,4-Difluoro-N-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide (CAS 2640352-97-0)
- 5,5-Difluoro-3-iodo-1,5,6,7-tetrahydro-4H-indol-4-one (CAS 2755401-98-8)
- Methyl 2,4-difluoro-5-iodobenzoate (CAS 1113050-16-0)
- Methyl 2,3-difluoro-5-iodobenzoate (CAS 1163692-49-6)
Recommended Standards
- 3-(Boc-amino)-4-(4-fluorophenyl)butyric Acid (CAS 683219-73-0)
- 4-(2-Fluorobenzyl)-6,7-dimethoxyisoquinoline (CAS 61190-18-9)
- 2,5-Bis(4-fluorophenyl)thiophene-3-carbonitrile (CAS 908588-07-8)
- 4-(3-Fluorobenzyl)-6,7-dimethoxyisoquinoline (CAS 61190-19-0)
- {4-[(4-methylphenyl)sulfanyl]-3-nitrophenyl}methyl N-(3,4-dichlorophenyl)carbamate (CAS 320424-10-0)
- N-(4-Bromo-2-chlorophenyl)tetrahydro-2H-pyran-4-amine (CAS 1056465-04-3)
- 2-(3,5-Difluoro-2-nitrophenyl)acetic acid (CAS 130400-45-2)
- Estradiol Impurity 43 (CAS 19590-55-7)
- Nebivolol Impurity 78 (CAS CATO-C4X-196878)
- 2-(2-Azaspiro[3.3]heptan-6-yloxy)-1-morpholinoethanone (CAS 1707364-58-6)
- 1-(tert-Butylsulfonyl)-4-methylbenzene (CAS 5324-90-3)
- 5-Bromo-3,3-bis(2-bromoethyl)indolin-2-one (CAS 880079-37-8)
- 3-Phenyl-[1,2,4]triazolo[5,1-c][1,2,4]triazin-4-amine (CAS 521300-68-5)
- Insulin Degludec Impurity 8 (CAS CATO-C4X-21578)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com