N-(3-Chloro-4-hydroxyphenyl)methanesulfonamide CAS 321962-11-2
| CAS No. | 321962-11-2 |
| Molecular Formula | C7H8ClNO3S |
| Molecular Weight | 221.66 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of N-(3-Chloro-4-hydroxyphenyl)methanesulfonamide is closely related to an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies N-(3-Chloro-4-hydroxyphenyl)methanesulfonamide (CAS 321962-11-2), a certified reference material (molecular formula C7H8ClNO3S, MW 221.66 g/mol) for analytical method development and quality control.
Owing to an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system, N-(3-Chloro-4-hydroxyphenyl)methanesulfonamide is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 221.66 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures N-(3-Chloro-4-hydroxyphenyl)methanesulfonamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H8ClNO3S |
| Molecular Weight | 221.66 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related N Standards
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Recommended Standards
- Methanesulfonicacid2-chloropyridin-4-ylmethylester (CAS 680569-47-5)
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- Ethyl 2-chloro-4-(hydroxymethyl)thiazole-5-carboxylate (CAS 907545-53-3)
- 1319AF 2-Chloro-N-(5-methoxymethyl-[1,3,4]thiadiazol-2-yl)-acetamide 876710-55-3 C6H8ClN3O2S (CAS 876710-55-3)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com