4-(((4-Chlorophenyl)sulfonamido)methyl)-5,5,5-trifluoropentanoic acid CAS 321970-80-3

Description

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

4-(((4-Chlorophenyl)sulfonamido)methyl)-5,5,5-trifluoropentanoic acid (CAS 321970-80-3), molecular formula C12H13ClF3NO4S and molecular weight 359.75 g/mol, is a CATO reference standard with documented purity and traceability.

4-(((4-Chlorophenyl)sulfonamido)methyl)-5,5,5-trifluoropentanoic acid (C12H13ClF3NO4S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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