7-(3,5-Dimethyl-1H-pyrazol-1-yl)-2,4-bis(trifluoromethyl)-1,8-naphthyridine CAS 321998-05-4
| CAS No. | 321998-05-4 |
| Molecular Formula | C15H10F6N4 |
| Molecular Weight | 360.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 7-(3,5-Dimethyl-1H-pyrazol-1-yl)-2,4-bis(trifluoromethyl)-1,8-naphthyridine (C15H10F6N4) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
7-(3,5-Dimethyl-1H-pyrazol-1-yl)-2,4-bis(trifluoromethyl)-1,8-naphthyridine (CAS 321998-05-4), molecular formula C15H10F6N4 and molecular weight 360.26 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 7-(3,5-Dimethyl-1H-pyrazol-1-yl)-2,4-bis(trifluoromethyl)-1,8-naphthyridine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C15H10F6N4 |
| Molecular Weight | 360.26 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
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Recommended Standards
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- n-(2-Morpholinoethyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide (CAS 787591-39-3)
- 5-Phenyloxazolidine-2,4-dione (CAS 5841-63-4)
- 3-Amino-1-(4-methoxyphenyl)-1H-pyrazole-4-carboxylic acid (CAS 1624260-88-3)
- (3S)-3-fluoropyrrolidin-2-one (CAS 1817738-17-2)
- Perfluorophenyl acetate (CAS 19220-93-0)
- 1-((9H-fluoren-9-yl)methyl) 2-(4-nitrophenyl) (S)-pyrrolidine-1,2-dicarboxylate (CAS 71989-32-7)
- N-(1-(4-ethylphenyl)-3-(4-(2-fluorophenyl)piperazin-1-yl)-3-oxopropyl)-2,2,2-trifluoroacetamide (CAS 866019-26-3)
- Atracurium Impurity 67 (CAS CATO-C4X-185067)
- Ethyl 2-[(chloroacetyl)amino]-6-methyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate (CAS 1221750-39-5)
- 3-(3-Nitro-1h-1,2,4-triazol-1-yl)adamantane-1-carboxylic acid (CAS 445228-83-1)
- Des-[Gly]31-Semaglutide(x TFA Salt) (CAS 873874-39-6(free base))
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