3-(Chlorodifluoromethyl)-5-methyl-1h-pyrazole CAS 321998-14-5
| CAS No. | 321998-14-5 |
| Molecular Formula | C5H5ClF2N2 |
| Molecular Weight | 166.56 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures 3-(Chlorodifluoromethyl)-5-methyl-1h-pyrazole under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
3-(Chlorodifluoromethyl)-5-methyl-1h-pyrazole (CAS 321998-14-5), molecular formula C5H5ClF2N2 and molecular weight 166.56 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 3-(Chlorodifluoromethyl)-5-methyl-1h-pyrazole (C5H5ClF2N2) is characterized by a nitrile group, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C5H5ClF2N2 |
| Molecular Weight | 166.56 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Chlorodifluoromethyl Standards
- 3-(Chlorodifluoromethyl)pyridine (CAS 76541-43-0)
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Recommended Standards
- 2-Chloroethyl n-carbamoylcarbamate (CAS 88795-43-1)
- 3-Cyanopicolinoyl chloride (CAS 856837-02-0)
- 2-Chloro-6-formylisonicotinonitrile (CAS 448907-74-2)
- 4-Chloro-6-formylpicolinonitrile (CAS 448907-58-2)
- 2-(5-Chloropyrimidin-2-yl)acetonitrile (CAS 1227581-41-0)
- 3-(3-(3-(4-hydroxyphenyl)) (CAS CATO-C3D-262208)
- N-(cyclohexylmethyl)propionamide (CAS 25079-97-4)
- 6,8-difluoro-[1,2,4]triazolo[1,5-a]pyridin-2-amine (CAS 1643856-61-4)
- Lutetium(III) sulfate hydrate (CAS 20814-12-4)
- 4-(tert-Butyl)picolinimidamide (CAS 949077-33-2)
- Methyl 2-(3-methylpyridin-2-yl)acetate (CAS 1092477-78-5)
- 7-Bromo-6-chloro-4-quinazolinone (CAS 17518-98-8)
- N-(hydrazinecarbonothioyl)pivalamide (CAS 914347-05-0)
- [14-31]-Semaglutide (CAS CATO-C4X-2226262)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com