(R)-2-(4-Fluorophenyl)-2-hydroxyacetic Acid CAS 32222-45-0
| CAS No. | 32222-45-0 |
| Molecular Formula | C8H7FO3 |
| Molecular Weight | 170.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of (R)-2-(4-Fluorophenyl)-2-hydroxyacetic Acid (C8H7FO3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
(R)-2-(4-Fluorophenyl)-2-hydroxyacetic Acid (CAS 32222-45-0) is a high-purity analytical reference standard with the molecular formula C8H7FO3 and a molecular weight of 170.14 g/mol.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures (R)-2-(4-Fluorophenyl)-2-hydroxyacetic Acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H7FO3 |
| Molecular Weight | 170.14 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1966 |
| Halogen Content | F-containing |
Related R Standards
- (S)-2-(2-Fluorophenyl)-2-hydroxyacetic acid (CAS 175134-34-6)
- (S)-2-(4-Fluorophenyl)-2-hydroxyacetic acid (CAS 52923-25-8)
- 2-(2-Fluorophenyl)-2-hydroxyacetic acid (CAS 389-31-1)
- 2-(3-Fluorophenyl)-2-hydroxyacetic acid (CAS 395-05-1)
- 2-(2-Fluorophenyl)propane-1,3-diol (CAS 1267313-28-9)
- 2-(4-fluorophenyl)-2-methoxyethan-1-ol (CAS 1785506-03-7)
- 2-(3-fluorophenyl)propane-1,3-diol (CAS 220469-27-2)
- 2-(4-Fluorophenyl)-1,3-propanediol (CAS 204201-52-5)
Recommended Standards
- (5-Fluoro-4-methyl-2-nitrophenyl)amine (CAS 428871-69-6)
- (R)-2-Fluoromandelic acid (CAS 32222-48-3)
- (4-Fluoro-3-nitrophenyl)methanamine (CAS 771581-73-8)
- (3-Fluorophenoxy)acetic Acid (CAS 404-98-8)
- 2-Chloro-5-((6-methoxy-7-(2-methoxyethoxy)quinazolin-4-yl)amino)cyclohexa-2,5-diene-1,4-dione (CAS 870959-62-9)
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- 3-Ethoxy-5-methyl-1H-pyrazole hydrochloride (CAS 1263988-40-4)
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- 2-((1H-1,2,4-Triazol-3-yl)amino)acetohydrazide (CAS 26275-48-9)
- 4-O-(2,3,4,6-TEtra-o-acetyl-beta-d-galactopyranosyl)-1,2,3,6-tetra-o-acetyl-beta-d-thioglucopyranose (CAS 1820576-07-5)
- 1,4-Dithiine (CAS 290-79-9)
- 5-Hydroxy-2-(trifluoromethyl)benzamide (CAS 1243460-65-2)
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