5-Phenyl-7H-thiazolo[3,2-a]pyrimidin-7-one CAS 32278-40-3

Purity 97%+In StockPharmaceutical Standards
CAS No.32278-40-3
Molecular FormulaC12H8N2OS
Molecular Weight228.27 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

5-Phenyl-7H-thiazolo[3,2-a]pyrimidin-7-one CAS 32278-40-3 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 228.27 g/mol gives 5-Phenyl-7H-thiazolo[3,2-a]pyrimidin-7-one distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

5-Phenyl-7H-thiazolo[3,2-a]pyrimidin-7-one (CAS 32278-40-3) is a high-purity analytical reference standard with the molecular formula C12H8N2OS and a molecular weight of 228.27 g/mol.

5-Phenyl-7H-thiazolo[3,2-a]pyrimidin-7-one (C12H8N2OS) contains a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage. Its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC12H8N2OS
Molecular Weight228.27 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)10.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1966
Nitrogen Atoms2
Sulfur Atoms1

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