7-(chloromethyl)quinazolin-4-amine CAS 323591-38-4
| CAS No. | 323591-38-4 |
| Molecular Formula | C9H8ClN3 |
| Molecular Weight | 193.63 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 7-(chloromethyl)quinazolin-4-amine is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
7-(chloromethyl)quinazolin-4-amine (CAS 323591-38-4) is a high-purity analytical reference standard with the molecular formula C9H8ClN3 and a molecular weight of 193.63 g/mol.
Structurally, 7-(chloromethyl)quinazolin-4-amine (C9H8ClN3) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 7.0, corresponding to approximately 7 ring(s) or double-bond equivalent(s). With a molecular weight of 193.63 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H8ClN3 |
| Molecular Weight | 193.63 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related chloromethyl Standards
- 5-(chloromethyl)-3-phenylisoxazole (CAS 1011-37-6)
- 5-Chloromethyl-8-hydroxyquinoline hydrochloride, 97% (CAS 10136-57-9)
- 1-(2-(Chloromethyl)phenyl)-1H-1,2,4-triazole (CAS 1038975-25-5)
- 2-(5-Chloromethyl-1H-imidazol-2-yl)pyridine (CAS 1053657-25-2)
- 2-(Chloromethyl)-4-phenyloxazole (CAS 110704-37-5)
- 5-(chloromethyl)-1-phenyl-1H-1,2,4-triazole (CAS 114370-76-2)
- 3-(4-(Chloromethyl)phenyl)isoxazole (CAS 1187532-70-2)
- 3-(Chloromethyl)-1,2-dihydroisoquinolin-1-one (CAS 1258640-51-5)
Recommended Standards
- 6'-Chlorospiro[cyclopropane-1,3'-indolin]-2'-one (CAS 83419-49-2)
- 7-Chloro-1-methyl-1H-indole-3-carbaldehyde (CAS 620175-79-3)
- 6-Chloro-8-methylquinolin-2(1H)-one (CAS 701289-61-4)
- 7-Chloro-3-methyl-1,2-dihydroisoquinolin-1-one (CAS 24188-75-8)
- 1-(2-(Azepan-1-yl)ethyl)guanidine sulfate(2:1) (CAS 7770-99-2)
- 4-Methyl-5-(3-(thiophen-2-yl)-6-(trifluoromethyl)thieno[3,2-b]pyridin-2-yl)-2,4-dihydro-3H-1,2,4-triazole-3-thione (CAS 477854-06-1)
- Tert-butyl dibutylcarbamate (CAS 197958-46-6)
- 4-[(phenylcarbamoyl)amino]benzoic acid (CAS 5467-09-4)
- Flecainide Impurity 5 (CAS CATO-C4X-25465)
- 6-Azatricyclo[5.2.0.02,5]nonane (CAS 132804-27-4)
- 2-(4-Fluorophenyl)-N-(5-(1-methyl-1H-pyrazol-5-yl)-1,3,4-oxadiazol-2-yl)acetamide (CAS 1171184-71-6)
- 3-(3,5-Dimethoxyphenyl)-1-propene 64118-89-4 7276AE C11H14O2 (CAS 64118-89-4)
- Xanthosine (CAS 146-80-5)
- Palmitoyl Tripeptide-5 TFA (CAS 623172-55-4（free base）)
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