2-(3-Hydroxyphenyl)quinoline-4-carboxylic acid CAS 32366-58-8

Purity 97%+In StockPharmaceutical Standards
CAS No.32366-58-8
Molecular FormulaC16H11NO3
Molecular Weight265.26 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-(3-Hydroxyphenyl)quinoline-4-carboxylic acid CAS 32366-58-8 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 265.26 g/mol gives 2-(3-Hydroxyphenyl)quinoline-4-carboxylic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

2-(3-Hydroxyphenyl)quinoline-4-carboxylic acid (CAS 32366-58-8), molecular formula C16H11NO3 and molecular weight 265.26 g/mol, is a CATO reference standard with documented purity and traceability.

Structurally, 2-(3-Hydroxyphenyl)quinoline-4-carboxylic acid (C16H11NO3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 12.0, corresponding to approximately 12 ring(s) or double-bond equivalent(s). With a molecular weight of 265.26 g/mol, it falls into the medium-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC16H11NO3
Molecular Weight265.26 g/mol
AppearancePale yellow to yellow crystalline powder
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)12.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1966
Nitrogen Atoms1

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