Canagliflozin Impurity 34 CAS 32384-65-9

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.32384-65-9
Molecular FormulaC18H42O6Si4
Molecular Weight466.86 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Canagliflozin Impurity 34 CAS 32384-65-9 chemical structure

Description

The occurrence of Canagliflozin Impurity 34 is closely related to a carboxylic acid group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

CATO supplies Canagliflozin Impurity 34 (CAS 32384-65-9), a pharmacopoeial impurity reference standard (molecular formula C18H42O6Si4, MW 466.86 g/mol) used for the identification and quantification of trace impurities in APIs.

The molecular framework of Canagliflozin Impurity 34 (C18H42O6Si4) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development.

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC18H42O6Si4
Molecular Weight466.86 g/mol
Purity>95%
StorageStore at room temperature, keep sealed and dry
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityStable under recommended storage conditions
Degree of Unsaturation (DBE)-2.0
CAS Registry Year (est.)1966

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