3-[(3R,4R)-3-(Hydroxymethyl)-8-methoxy-3,4-dihydro-2H-1-benzopyran-4-yl]-3-methyl-1-phenylurea CAS 324009-17-8
| CAS No. | 324009-17-8 |
| Molecular Formula | C19H22N2O4 |
| Molecular Weight | 342.39 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
3-[(3R,4R)-3-(Hydroxymethyl)-8-methoxy-3,4-dihydro-2H-1-benzopyran-4-yl]-3-methyl-1-phenylurea (CAS 324009-17-8), molecular formula C19H22N2O4 and molecular weight 342.39 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 3-[(3R,4R)-3-(Hydroxymethyl)-8-methoxy-3,4-dihydro-2H-1-benzopyran-4-yl]-3-methyl-1-phenylurea (C19H22N2O4) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C19H22N2O4 |
| Molecular Weight | 342.39 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 2 |
Recommended Standards
- 3-[(2-PHenylquinolin-4-yl)carbonyl]-1-vinylpyrrolidin-2-one (CAS 910442-92-1)
- 3-[tert-butoxycarbonyl-(tert-butoxycarbonylamino)amino]bicyclo[1.1.1]pentane-1-carboxylic acid (CAS 2538602-45-6)
- 3,4-Di(furan-2-yl)-1-(pyridin-2-yl)-5,6,7,8-tetrahydroisoquinoline (CAS 692729-85-4)
- 3-Fluoro-N-(4-(4-methoxy-3-methylphenyl)thiazol-2-yl)benzamide (CAS 476283-24-6)
- 1-(4-Methoxybenzyl)pyrrolidine-3-carboxylic acid (CAS 1086375-34-9)
- 2-Chloro-N,N-diethylbenzenesulfonamide (CAS 858647-38-8)
- 6-(Quinolin-3-yl)hexan-1-amine (CAS 88940-51-6)
- 1-Allyl-6-iodo-1H-benzo[d][1,3]oxazine-2,4-dione (CAS 1131605-41-8)
- N,N-dimethyl-2-(2-((methylamino)methyl)phenoxy)ethan-1-amine (CAS 884507-33-9)
- (2E,4E)-2,4-Decadienoic Acid Methyl Ester (CAS 7328-33-8)
- Gliclazide EP Impurity F (CAS 1076198-18-9)
- N-methyl-N-[(3S)-piperidin-3-yl]methanesulfonamide (CAS 1419075-89-0)
- (1R,3r,5S)-Ipratropium Impurity 35 (CAS 88607-15-2)
- Peptide Impurity 11 X TFA Salt (CAS CATO-CPTD788811)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com