5-Methoxy-6-nitropicolinic acid CAS 324028-85-5
| CAS No. | 324028-85-5 |
| Molecular Formula | C7H6N2O5 |
| Molecular Weight | 198.13 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-Methoxy-6-nitropicolinic acid.
5-Methoxy-6-nitropicolinic acid (CAS 324028-85-5), molecular formula C7H6N2O5 and molecular weight 198.13 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage, 5-Methoxy-6-nitropicolinic acid is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 198.13 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H6N2O5 |
| Molecular Weight | 198.13 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 2 |
Related Methoxy Standards
- 6-Methoxy-5-nitro-3-pyridinecarboxylic acid (CAS 1211516-51-6)
- 6-Methoxy-3-nitropicolinic acid (CAS 1350475-33-0)
- 4-Methoxy-5-nitropicolinic acid (CAS 1416801-26-7)
- 1-Methoxy-2,3-dinitrobenzene (CAS 16315-07-4)
- 4-Methoxy-5-nitronicotinic acid (CAS 2089326-23-6)
- 3-Methoxy-3-(trifluoromethyl)cyclobutane-1-carboxylic acid (CAS 2378501-18-7)
- Methyl 5-(2-methoxy-2-oxoethyl)furan-2-carboxylate (CAS 1087784-37-9)
- METHYL 2-(2-METHOXY-2-OXOETHYL)-3-FUROATE (CAS 162337-80-6)
Recommended Standards
- 5-Amino-2-hydroxy-3-nitrobenzoic acid (CAS 945-20-0)
- 6,7-Difluoroquinazoline-2,4(1H,3H)-dione (CAS 769158-54-5)
- 5,6-Difluoro-3-nitro-1H-indole (CAS 2138239-73-1)
- 6,7-Difluoroquinoxaline-2,3(1H,4H)-dione (CAS 91895-29-3)
- N-(2-Hydroxyethyl)-4-(6-((4-(trifluoromethoxy)phenyl)amino)pyrimidin-4-yl)benzamide (CAS 778274-97-8)
- 1-(3-Methyl-1H-indol-2-yl)ethanone (CAS 16244-23-8)
- Ethyl 2-(3-bromophenyl)sulfanylpropanoate (CAS 1341335-88-3)
- 59457-26-0 1-Chloro-1,2-benziodoxol-3-one MFCD28411322 NSC191950/ 1-chloro-1lambda3,2-benziodoxol-3(1H)-one (CAS 59457-26-0)
- (3R)-2-Methylpentan-3-ol (CAS 63814-74-4)
- 8-ethynyl-[1,2,4]triazolo[4,3-a]pyridine (CAS 2767259-28-7)
- 6,7-Difluoro-1,2,3,4-tetrahydroquinolin-3-amine (CAS 2750639-62-2)
- Sodium 5-amino-2-nitrobenzoate (CAS 1951444-76-0)
- 6-(3-Fluorophenyl)-2-thioxo-2,3-dihydropyrimidin-4(1H)-one (CAS 33297-99-3)
- FMRF Amide Related Peptide. (CAS 149471-12-5)
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