2-Chloro-4-nitro-N-(thiazol-2-yl)benzamide CAS 324058-89-1
| CAS No. | 324058-89-1 |
| Molecular Formula | C10H6ClN3O3S |
| Molecular Weight | 283.69 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-Chloro-4-nitro-N-(thiazol-2-yl)benzamide.
2-Chloro-4-nitro-N-(thiazol-2-yl)benzamide (CAS 324058-89-1) is a high-purity analytical reference standard with the molecular formula C10H6ClN3O3S and a molecular weight of 283.69 g/mol.
The molecular framework of 2-Chloro-4-nitro-N-(thiazol-2-yl)benzamide (C10H6ClN3O3S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-Chloro-4-nitro-N-(thiazol-2-yl)benzamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H6ClN3O3S |
| Molecular Weight | 283.69 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Chloro Standards
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Recommended Standards
- Ethyl 5-amino-4-chloro-1-(4-fluorophenyl)-1H-pyrazole-3-carboxylate (CAS 1427011-67-3)
- Ethyl 5-amino-1-(4-chloro-2-fluorophenyl)-1H-pyrazole-4-carboxylate (CAS 1416339-26-8)
- 5-Amino-N-(3-chloro-4-fluorophenyl)-3-ethylisoxazole-4-carboxamide (CAS 632291-66-8)
- N-((4-chlorobenzoyl)oxy)-1,2,3-thiadiazole-4-carboxamide (CAS 341965-59-1)
- 1-(2,5-difluorophenyl)-2,2-difluoroethan-1-amine (CAS 1038724-69-4)
- 1,3-Di(pyren-1-yl)benzene (CAS 1644438-20-9)
- N-methyl-N-phenylmorpholin-3-amine (CAS 1489640-57-4)
- 1-(4-Methoxybenzyl)-4-methyl-1H-pyrazol-5-amine (CAS 1152526-72-1)
- Saxagliptin Impurity 12 (CAS 1564265-94-6)
- Tadalafil Impurity 178 (CAS CATO-C4X-1087178)
- N-Nitroso Metformin Impurity 1 (CAS CATO-C4X-1220533)
- 4-Methyl-7-(piperazin-1-yl)-2H-chromen-2-one hydrochloride (CAS 1427502-00-8)
- 2-(5-Methyl-3-(thiophen-2-yl)-1H-pyrazol-4-yl)acetic acid (CAS 1380440-85-6)
- Tirzepatide Impurity 35 (CAS CATO-C4X-324035)
Why CATO?
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