4-Fluoro-2-iodothiophene CAS 32431-67-7
| CAS No. | 32431-67-7 |
| Molecular Formula | C4H2FIS |
| Molecular Weight | 228.03 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
4-Fluoro-2-iodothiophene (CAS 32431-67-7), molecular formula C4H2FIS and molecular weight 228.03 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 4-Fluoro-2-iodothiophene (C4H2FIS) is characterized by sulfur-containing functionality, fluorine/iodine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), 4-Fluoro-2-iodothiophene meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C4H2FIS |
| Molecular Weight | 228.03 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1966 |
| Halogen Content | F/I-containing |
| Sulfur Atoms | 1 |
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