1,4-Bis[(3-Iodophenyl)carbonyl]piperazine CAS 324776-77-4
| CAS No. | 324776-77-4 |
| Molecular Formula | C18H16I2N2O2 |
| Molecular Weight | 546.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures 1,4-Bis[(3-Iodophenyl)carbonyl]piperazine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
1,4-Bis[(3-Iodophenyl)carbonyl]piperazine (CAS 324776-77-4) is a high-purity analytical reference standard with the molecular formula C18H16I2N2O2 and a molecular weight of 546.14 g/mol.
1,4-Bis[(3-Iodophenyl)carbonyl]piperazine (C18H16I2N2O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, iodine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C18H16I2N2O2 |
| Molecular Weight | 546.14 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | I-containing |
| Nitrogen Atoms | 2 |
Related Bis Standards
- 2-[2-[(4-Iodophenyl)amino]-2-oxoethoxy]-N-[2-(methylphenylamino)-2-oxoethyl]-benzamide (CAS 1462267-07-7)
- 4-Iodophenyl 2-acetamido-3-4-6-tri-O-acetyl-2-deoxy-β-D-glucopyranoside (CAS 38229-75-3)
- 4-Iodophenyl 2,3,4-Tri-O-acetyl-|A-D-glucuronide Methyl Ester 4-Iodophenyl-|A-D-glucopyranosiduronic Acid Methyl Ester Triacetate 490028-18-7 (CAS 490028-18-7)
- 2-((18-(4-Iodophenyl)octadecyl)oxy)tetrahydro-2H-pyran (CAS 347143-82-2)
- 2-(4-((4-Iodophenyl)sulfonyl)piperazin-1-yl)-N-(4-methoxyphenyl)-6-methylpyrimidin-4-amine (CAS 946364-60-9)
- 4-(bis(4-Iodophenyl)amino)benzaldehyde (CAS 808758-81-8)
- 2-((4-(N-(4-iodophenyl)sulfamoyl)phenyl)carbamoyl)benzoic acid (CAS 444147-63-1)
- Ethyl 6-(4-Iodophenyl)-1-(4-methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate (CAS 473927-64-9)
Recommended Standards
- 1H,1H,2H-Perfluoro-1-dodecene (CAS 30389-25-4)
- Amiodarone EP Impurity D (CAS 1951-26-4)
- Haloperidol Decanoate N-Oxide (CAS 2749298-36-8)
- 1-(3,5-Bis(perfluorobutyl)-1H-pyrazol-1-yl)ethan-1-one (CAS 247170-28-1)
- 2-Methyl-1-(1,1,2,2-tetrafluoroethoxy)propane (CAS 18180-34-2)
- 2-Chloro-N-isopropyl-N-((1-methylpyrrolidin-3-yl)methyl)acetamide (CAS 1353974-83-0)
- 3-(Piperidin-3-yl)-1,3-dihydro-2h-imidazo[4,5-b]pyridin-2-one (CAS 1784243-34-0)
- Methyl 2-Bromo-3,6-dimethoxybenzoate, 97% (CAS 327163-77-9)
- 3-[4-(trifluoromethyl)phenyl]but-2-enoic acid (CAS 7386-61-0)
- tert-Butyl (1R*,4R*)-4-(2-methoxyacetamido)cyclohexylcarbamate (CAS 1011530-87-2)
- 2-Amino-4-(3-chloropropoxy)-5-methoxybenzonitrile (CAS 1122661-16-8)
- 1-Bromo-2,4-dichlorobenzene (CAS 1193-72-2)
- (S)-tert-Butyl 2-((2-chloro-N-isopropylacetamido)methyl)pyrrolidine-1-carboxylate (CAS 1354002-25-7)
- Angiotensin II Antipeptide (CAS 121379-63-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com