4,4,5,5-Tetramethyl-2-[3-(trifluoromethyl)phenyl]-1,3,2-dioxaborolane CAS 325142-82-3
| CAS No. | 325142-82-3 |
| Molecular Formula | C13H16BF3O2 |
| Molecular Weight | 272.07 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 4,4,5,5-Tetramethyl-2-[3-(trifluoromethyl)phenyl]-1,3,2-dioxaborolane (C13H16BF3O2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
4,4,5,5-Tetramethyl-2-[3-(trifluoromethyl)phenyl]-1,3,2-dioxaborolane (CAS 325142-82-3) is a high-purity analytical reference standard with the molecular formula C13H16BF3O2 and a molecular weight of 272.07 g/mol.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4,4,5,5-Tetramethyl-2-[3-(trifluoromethyl)phenyl]-1,3,2-dioxaborolane meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H16BF3O2 |
| Molecular Weight | 272.07 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
Related Tetramethyl Standards
- 4,4,5,5-Tetramethyl-2-(2-(trifluoromethyl)phenyl)-1,3,2-dioxaborolane (CAS 1073339-21-5)
- 6-(Tetramethyl-1,3,2-dioxaborolan-2-yl)chromen-2-one (CAS 1408287-07-9)
- 8-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-4H-chromen-4-one (CAS 1655495-95-6)
- 6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-4h-chromen-4-one (CAS 928773-42-6)
- 7-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-4H-chromen-4-one (CAS 517874-20-3)
- 6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)quinazolin-4(3H)-one (CAS 1009303-58-5)
- 7-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phthalazin-1(2H)-one (CAS 1009303-60-9)
- 2-[3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-1,3,4-oxadiazole (CAS 1186334-84-8)
Recommended Standards
- 4-(Aminomethyl)-6-bromo-5-fluorophthalazin-1(2H)-one (CAS 2836224-00-9)
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- 3,4,5-tris(trifluoromethyl)-1H-pyrazole (CAS 19968-20-8)
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- 4-Bromoquinoline-3-carboxylic acid (CAS 1378260-46-8)
- Fmoc-Asp(OMpe)-Asp(OMpe)-OH (CAS CATO-CPTD788968)
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- Ethyl 5-fluoro-6-methylnicotinate (CAS 1379210-48-6)
- 2-((2-Oxo-2-phenylethyl)thio)nicotinaldehyde (CAS 887577-13-1)
- 5-(3-Methoxyphenyl)pyridin-2-amine (CAS 893738-18-6)
- N-(4-(N-(1-(Ethylsulfonyl)-1,2,3,4-tetrahydroquinolin-6-yl)sulfamoyl)phenyl)butyramide (CAS 946347-87-1)
- Ethyl 3-[(2-methoxyethyl)amino]propanoate (CAS 66092-67-9)
- 2-(4-Chloro-3-ethylphenyl)propan-2-ol (CAS 1379342-47-8)
- Experimental Allergic Encephalitogenic Peptide (CAS 29705-92-8)
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