2,6-Dibromo-3,5-difluoroisonicotinic acid CAS 325461-60-7
| CAS No. | 325461-60-7 |
| Molecular Formula | C6HBr2F2NO2 |
| Molecular Weight | 316.88 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2,6-Dibromo-3,5-difluoroisonicotinic acid.
2,6-Dibromo-3,5-difluoroisonicotinic acid (CAS 325461-60-7) is a high-purity analytical reference standard with the molecular formula C6HBr2F2NO2 and a molecular weight of 316.88 g/mol.
The molecular framework of 2,6-Dibromo-3,5-difluoroisonicotinic acid (C6HBr2F2NO2) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 2,6-Dibromo-3,5-difluoroisonicotinic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C6HBr2F2NO2 |
| Molecular Weight | 316.88 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 1 |
Related Dibromo Standards
- 1,4-Dibromo-2,3-difluoro-5-nitrobenzene (CAS 1360726-52-8)
- 2,4-Dibromo-1,5-difluoro-3-nitrobenzene (CAS 144450-58-8)
- 2,3-Dibromo-5,6-difluoronitrobenzene (CAS 1481-57-8)
- 1,2-Dibromo-3,5-difluoro-4-nitrobenzene (CAS 1803715-37-8)
- 1,3-Dibromo-2,5-difluoro-4-nitrobenzene (CAS 1803789-51-6)
- 1,3-Dibromo-2,4-difluoro-6-nitrobenzene (CAS 1803835-24-6)
- 1,5-Dibromo-2,4-difluoro-3-nitrobenzene (CAS 1804413-71-5)
- 1,4-Dibromo-3,5-difluoro-2-nitrobenzene (CAS 1804938-00-8)
Recommended Standards
- 1,4-Dibromo-2,5-difluoro-3-nitrobenzene (CAS 702640-58-2)
- 4-Bromo-5-fluoro-2-iodophenol (CAS 1226879-58-8)
- 5-Bromo-4-iodo-1H-pyrazole-3-carboxylic acid (CAS 1934264-98-8)
- 4-Bromo-2-fluoro-6-iodophenol (CAS 1228093-50-2)
- phenyl(pyrrolidin-2-yl)methanol (CAS 113864-94-1)
- 1,3-Cyclohexanedione, 2-(cyclopropylcarbonyl)- (CAS 288258-62-8)
- Benzyl isopropyl(2-(methylamino)cyclohexyl)carbamate (CAS 1353953-55-5)
- 1-(5-Bromo-2-chlorophenyl)-2,2,2-trifluoroethan-1-ol (CAS 1692004-40-2)
- PD 144418 Oxalate (CAS 154130-99-1)
- 2-(Difluoromethyl)-5-fluoro-3-hydroxy-6-methylpyridine (CAS 1805502-85-5)
- Ethyl 1-(tert-butyl)-4-(hydroxymethyl)-1H-pyrazole-3-carboxylate (CAS 1374258-07-7)
- Butorphanol Tartrate (CAS 58786-99-5)
- Ethyl [(tert-butoxycarbonyl)(3-methyl-5-nitropyridin-2-yl)amino](oxo)acetate (CAS 1283402-63-0)
- Semaglutide Impurity 189 (CAS CATO-C4X-2226189)
Why CATO?
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