Bis[3,5-bis(1,1-dimethylethyl)phenyl]phosphine oxide CAS 325773-65-7

Purity 97%+In StockPharmaceutical Standards
CAS No.325773-65-7
Molecular FormulaC28H43OP
Molecular Weight426.61 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

Bis[3,5-bis(1,1-dimethylethyl)phenyl]phosphine oxide CAS 325773-65-7 chemical structure

Description

Bis[3,5-bis(1,1-dimethylethyl)phenyl]phosphine oxide (CAS 325773-65-7) is a high-purity analytical reference standard with the molecular formula C28H43OP and a molecular weight of 426.61 g/mol.

Owing to a steroid core, organophosphorus functionality, a hydroxyl group, an ether linkage, Bis[3,5-bis(1,1-dimethylethyl)phenyl]phosphine oxide is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 426.61 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC28H43OP
Molecular Weight426.61 g/mol
AppearanceOff-white to pale yellow crystalline powder
Purity97%+
StorageStore at room temperature, protect from light
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)7.5
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025

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