(4-Chloro-2-fluoro-5-formylphenyl)boronic acid CAS 325786-27-4
| CAS No. | 325786-27-4 |
| Molecular Formula | C7H5BClFO3 |
| Molecular Weight | 202.38 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
(4-Chloro-2-fluoro-5-formylphenyl)boronic acid (CAS 325786-27-4) is a high-purity analytical reference standard with the molecular formula C7H5BClFO3 and a molecular weight of 202.38 g/mol.
(4-Chloro-2-fluoro-5-formylphenyl)boronic acid (C7H5BClFO3) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H5BClFO3 |
| Molecular Weight | 202.38 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
Related Chloro Standards
- 4-Chloro-3-fluoro-2-formylphenylboronic acid (CAS 1451392-90-7)
- 2-Chloro-6-fluoro-3-formylphenylboronic acid (CAS 1451392-95-2)
- 6-Chloro-2-fluoro-3-formylphenylboronic acid (CAS 1451393-10-4)
- 4-Chloro-2-fluoro-3-formylphenylboronic acid (CAS 1451393-44-4)
- 2-Chloro-3-fluoro-4-formylphenylboronic acid (CAS 2121514-97-2)
- (3-Chloro-4-hydroxy-5-methoxyphenyl)boronic acid (CAS 919496-57-4)
- 2-Chloro-3-iodoprop-1-ene (CAS 39557-31-8)
- 5-Chloro-3-(meththio)phenylboronic acid (CAS 1451392-52-1)
Recommended Standards
- 1,2-Bis(butylthio)ethyne (CAS 66566-76-5)
- 1,2-Dicyclopentyldisulfane (CAS 4485-78-3)
- 3-(Pent-4-en-1-ylthio)tetrahydro-2H-thiopyran (CAS 61704-43-6)
- (4-(Chlorocarbonyl)-3-fluorophenyl)boronic acid (CAS 1313712-87-6)
- 3-(Cyanomethyl)-5-(difluoromethyl)-4-methylpicolinonitrile (CAS 1806849-16-0)
- 5-Fluoro-3,4-dihydro-2H-1,4-benzoxazine (CAS 1067171-66-7)
- 6,7-Dihydro-5H-cyclopenta[b]pyridin-5-amine (CAS 535935-84-3)
- (R)-2-(4-Bromophenyl)-2-((tert-butoxycarbonyl)amino)acetic acid (CAS 1228570-47-5)
- 3-(4-Bromo-2-propylphenoxy)azetidine (CAS 1220027-80-4)
- Brexpiprazole Impurity 138 (CAS CATO-C4X-1131138)
- 1-(Pyrazolo[1,5-a]pyridin-3-ylmethyl)-3-(2-(trifluoromethyl)phenyl)urea (CAS 1396749-04-4)
- 3-Chloro-5H,6H,7H,8H-imidazo[1,2-a]pyrazine dihydrochloride (CAS 2034154-09-9)
- 1-(4-Methylbenzyl)pyrrolidin-3-ol (CAS 1044769-60-9)
- Liraglutide Impurity 30 (CAS CATO-C4X-199230)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com