6-(Trifluoromethyl)benzimidazole CAS 326-55-6
| CAS No. | 326-55-6 |
| Molecular Formula | C8H5F3N2 |
| Molecular Weight | 186.13 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 6-(Trifluoromethyl)benzimidazole meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
6-(Trifluoromethyl)benzimidazole (CAS 326-55-6), molecular formula C8H5F3N2 and molecular weight 186.13 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution, 6-(Trifluoromethyl)benzimidazole is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 186.13 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C8H5F3N2 |
| Molecular Weight | 186.13 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Trifluoromethyl Standards
- 4-(Trifluoromethyl)-1H-indazole (CAS 1000339-98-9)
- 2-(3-(Trifluoromethyl)pyridin-2-yl)acetonitrile (CAS 1000512-60-6)
- 2-(Trifluoromethyl)pyridine-3-acetonitrile (CAS 1000529-97-4)
- 2-(4-(Trifluoromethyl)pyridin-2-yl)acetonitrile (CAS 1000536-10-6)
- 2-(6-(Trifluoromethyl)pyridin-2-yl)acetonitrile (CAS 1000564-90-8)
- 3-(Trifluoromethyl)pyridine-5-acetonitrile (CAS 1000565-50-3)
- 4-(Trifluoromethyl)benzofuran (CAS 1065076-52-9)
- 4-(Trifluoromethyl)-7-azaindole (CAS 1092579-96-8)
Recommended Standards
- 6-(Methylamino)-5-nitropyrimidine-2,4(1H,3H)-dione (CAS 41964-42-5)
- 6-(Trifluoromethyl)imidazo[1,2-a]pyridine (CAS 936009-02-8)
- 5-Amino-2-(trifluoromethyl)benzonitrile (CAS 354814-19-0)
- 6-(Trifluoromethyl)indazole (CAS 954239-22-6)
- 3-(3,5-Dichlorophenyl)-2-hydroxypropanoic acid (CAS 1511336-39-2)
- 2-Amino-3-hydroxy-3-methylbutanoic Acid (CAS 2280-28-6)
- 4-Cyano-3-(4-methoxyphenyl)-5-(methylthio)thiophene-2-carboxylic acid (CAS 116493-07-3)
- 2-Chloro-n-[2-(thiophen-3-yl)ethyl]acetamide (CAS 135709-70-5)
- 3-(Furan-2-yl)-3,4-dihydro-2H-pyrrol-5-amine (CAS 773010-76-7)
- 2-(2-chlorofuran-3-yl)propanoic acid (CAS 1519129-23-7)
- methyl 5-[(tert-butoxy)methyl]-1,2-oxazole-3-carboxylate (CAS 1803583-17-6)
- 2-Ethyl-6-methylpyrazine (CAS 13925-03-6)
- methyl (3R,4S)-4-aminotetrahydrofuran-3-carboxylate hydrochloride (CAS 503168-08-9)
- Semaglutide impurity 58 (CAS CATO-C4X-222658)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com