4,4,4-Trifluoro-1-(thiophen-2-yl)butane-1,3-dione CAS 326-91-1

Purity 97%+In StockPharmaceutical Standards
CAS No.326-91-1
Molecular FormulaC8H5F3O2S
Molecular Weight222.18 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

4,4,4-Trifluoro-1-(thiophen-2-yl)butane-1,3-dione CAS 326-91-1 chemical structure

Description

The occurrence of 4,4,4-Trifluoro-1-(thiophen-2-yl)butane-1,3-dione is closely related to a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

4,4,4-Trifluoro-1-(thiophen-2-yl)butane-1,3-dione (CAS 326-91-1), molecular formula C8H5F3O2S and molecular weight 222.18 g/mol, is a CATO reference standard with documented purity and traceability.

4,4,4-Trifluoro-1-(thiophen-2-yl)butane-1,3-dione (C8H5F3O2S) contains a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 4,4,4-Trifluoro-1-(thiophen-2-yl)butane-1,3-dione meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC8H5F3O2S
Molecular Weight222.18 g/mol
Purity97%+
StorageStore at room temperature, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1957
Halogen ContentF-containing
Sulfur Atoms1

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