5-Chlorobenzofuran-3(2H)-one CAS 3261-05-0
| CAS No. | 3261-05-0 |
| Molecular Formula | C8H5ClO2 |
| Molecular Weight | 168.58 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-Chlorobenzofuran-3(2H)-one.
5-Chlorobenzofuran-3(2H)-one (CAS 3261-05-0), molecular formula C8H5ClO2 and molecular weight 168.58 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 5-Chlorobenzofuran-3(2H)-one (C8H5ClO2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 168.58 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 5-Chlorobenzofuran-3(2H)-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H5ClO2 |
| Molecular Weight | 168.58 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Cl-containing |
Related Chlorobenzofuran Standards
- 5-Chlorobenzofuran-6-ol (CAS 1352507-89-1)
- 2-Chlorobenzofuran-7-ol (CAS 1557704-82-1)
- 4-Chlorobenzofuran-5-ol (CAS 879093-12-6)
- 5-Chlorobenzofuran-7-amine (CAS 1260858-98-7)
- 3-Chlorobenzofuran-7-amine (CAS 379228-65-6)
- 5-Chlorobenzofuran-4-amine (CAS 412336-61-9)
- 7-chlorobenzofuran-3-one (CAS 3260-94-4)
- 6-chlorobenzofuran-7-amine (CAS 379230-43-0)
Recommended Standards
- 5-Chlorobenzo[d]oxazol-6-amine (CAS 916791-64-5)
- 5-Chloropyrazolo[1,5-a]pyrimidin-7-amine (CAS 245095-96-9)
- 5-Chlorobenzimidazol-2(3H)-one (CAS 2034-23-3)
- 6-Chloro-1,2-benzoxazol-3-amine (CAS 89692-53-5)
- Benzoic acid, 4-ethenyl-, 2,5-dioxo-1-pyrrolidinyl ester (CAS 97856-35-4)
- 2,3-Dichloro-5-methoxyquinoxaline (CAS 101870-68-2)
- 2-(4-Methoxy-6-methylpyridin-2-yl)ethan-1-amine (CAS 1393541-69-9)
- 4-Hydroxy-5-((4-methoxybenzyl)oxy)-1,4-dihydropyridine-2-carboxylic acid (CAS 1632286-08-8)
- Tert-butyl 4-(n,n-dimethylsulfamoyl)piperazine-1-carboxylate (CAS 253176-45-3)
- 4-(2-Chloro-4-fluorophenyl)-1H-pyrazol-5-amine, hydrochloride (CAS 1177279-79-6)
- 2-((Triphenylphosphoranylidene)amino)ethyl benzoate (CAS 179039-70-4)
- (2-(Trifluoromethyl)quinazolin-4-yl)proline (CAS 1008592-58-2)
- Diphenyl (hydroxy(naphthalen-1-yl)methyl)phosphonate (CAS 681455-07-2)
- Semaglutide Impurity 137 (x TFA Salt) (CAS CATO-C4X-2226137)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com