2-(4-Fluorophenyl)imidazo[1,2-a]pyridin-3-amine CAS 326883-87-8
| CAS No. | 326883-87-8 |
| Molecular Formula | C13H10FN3 |
| Molecular Weight | 227.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 2-(4-Fluorophenyl)imidazo[1,2-a]pyridin-3-amine (CAS 326883-87-8), a certified reference material (molecular formula C13H10FN3, MW 227.24 g/mol) for analytical method development and quality control.
The molecular framework of 2-(4-Fluorophenyl)imidazo[1,2-a]pyridin-3-amine (C13H10FN3) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C13H10FN3 |
| Molecular Weight | 227.24 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Fluorophenyl Standards
- 2-(3-Fluorophenyl)-1H-1,3-benzodiazol-5-amine (CAS 1016773-06-0)
- 1-(2-Fluorophenyl)-1h-1,3-benzodiazol-2-amine (CAS 1038303-09-1)
- 1-(4-Fluorophenyl)-1h-1,3-benzodiazol-2-amine (CAS 106461-31-8)
- 3-(2-Fluorophenyl)-1H-indazol-5-amine (CAS 1175859-35-4)
- 1-(4-Fluorophenyl)-3-methyl-1h-pyrazolo[4,3-b]pyridine (CAS 1383734-85-7)
- 4-(2-Fluorophenyl)-1H-indazol-3-amine (CAS 1715912-51-8)
- 2-(4-Fluorophenyl)-1h-1,3-benzodiazol-5-amine (CAS 863869-96-9)
- 3-(3-Fluorophenyl)-1H-indazol-7-amine (CAS 473410-09-2)
Recommended Standards
- 2-(carbamoylmethanesulfinyl)benzoic acid (CAS 682749-23-1)
- 2-(2-Hydroxyethyl)benzo[d]isothiazol-3(2H)-one 1,1-dioxide (CAS 6343-81-3)
- 2-[(2-Nitrophenyl)thio]acetic Acid Hydrazide (CAS 4871-40-3)
- 2-((2-Carboxyethyl)Thio)Nicotinic Acid (CAS 286472-02-4)
- 2-((1H-benzo[4,5]imidazo[2,1-c][1,2,4]triazol-3-yl)thio)propanoic acid (CAS 510764-59-7)
- tert-Butyl 2,5-diazaspiro[3.5]nonane-2-carboxylate (CAS 1246034-93-4)
- 4-((Phenylimino)methyl)phenol (CAS 2505-66-0)
- 4-Bromo-2,5-bis(trifluoromethyl)benzonitrile (CAS 1805971-70-3)
- n-(2-Chlorobenzyl)-1-methylpyrrolidin-3-amine (CAS 1248992-55-3)
- (s)-2-Amino-2-(2-chloro-6-nitrophenyl)ethan-1-ol (CAS 1212902-27-6)
- (R)-3-Amino-3-(pyridin-4-yl)propanoic acid hydrochloride (CAS 1192069-09-2)
- (2-(Allyloxy)-3-chloropyridin-4-yl)boronic acid (CAS 1987879-17-3)
- 2-((1-(Furan-2-ylmethyl)-5-phenyl-1H-imidazol-2-yl)thio)acetonitrile (CAS 930863-06-2)
- Semaglutide impurity 34 (CAS CATO-C4X-222634)
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