Ethyl 2-amino-4-(2-chloro-6-fluorophenyl)-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carboxylate CAS 326919-69-1
| CAS No. | 326919-69-1 |
| Molecular Formula | C18H17ClFNO4 |
| Molecular Weight | 365.78 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 365.78 g/mol gives Ethyl 2-amino-4-(2-chloro-6-fluorophenyl)-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carboxylate distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Ethyl 2-amino-4-(2-chloro-6-fluorophenyl)-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carboxylate (CAS 326919-69-1) is a high-purity analytical reference standard with the molecular formula C18H17ClFNO4 and a molecular weight of 365.78 g/mol.
Ethyl 2-amino-4-(2-chloro-6-fluorophenyl)-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carboxylate (C18H17ClFNO4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures Ethyl 2-amino-4-(2-chloro-6-fluorophenyl)-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carboxylate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H17ClFNO4 |
| Molecular Weight | 365.78 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
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Recommended Standards
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- 1-Benzyl-3-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrido[2,3-d]pyrimidine-6-sulfonyl chloride (CAS 1334147-57-7)
- 3-(Benzenesulfonyl)-4-methyl-6-phenyl-1-{[3-(trifluoromethyl)phenyl]methyl}-1,2-dihydropyridin-2-one (CAS 321431-33-8)
- (4Z)-2-Methyl-2,3-dihydro-4H-thieno[2,3-e][1,2]-thiazin-4-one oxime 1,1-dioxide (CAS 1030422-56-0)
- (R)-5,6-Dimethyl-7-(1-phenylethyl)-3,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one (CAS 177570-39-7)
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- 1-(2-Methoxyphenyl)-3-(2-methoxypyrimidin-5-yl)urea (CAS 1396870-40-8)
- 2-Methyl-4-nitro-1H-benzo[d]imidazol-5-ol (CAS 127025-81-4)
- 1-(2-Fluorophenyl)-2-methyl-1h-pyrrole (CAS 1354784-00-1)
- 3-(N-(2,4-difluorophenyl)sulfamoyl)-2-methylpropanoic acid (CAS 1018260-78-0)
- Semaglutide impurity 101 (CAS CATO-C4X-2226101)
Why CATO?
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