1,4-Dibromo-2,5-difluorobenzene CAS 327-51-5
| CAS No. | 327-51-5 |
| Molecular Formula | C6H2Br2F2 |
| Molecular Weight | 271.88 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 1,4-Dibromo-2,5-difluorobenzene (CAS 327-51-5), a certified reference material (molecular formula C6H2Br2F2, MW 271.88 g/mol) for analytical method development and quality control.
Owing to fluorine/bromine substitution, an aromatic ring system, 1,4-Dibromo-2,5-difluorobenzene is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 271.88 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H2Br2F2 |
| Molecular Weight | 271.88 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F/Br-containing |
Related Dibromo Standards
- 1,3-Dibromo-2,5-difluorobenzene (CAS 128259-68-7)
- 2,5-Dibromo-1,3-difluorobenzene (CAS 128259-71-2)
- 1,2-Dibromo-3,5-difluorobenzene (CAS 139215-43-3)
- 1,4-Dibromo-2,3-difluorobenzene (CAS 156682-52-9)
- 2,3-Dibromo-1,4-difluorobenzene (CAS 179737-33-8)
- 1,2-Dibromo-3,4-difluorobenzene (CAS 811713-01-6)
- 1,3-Dibromo-2,4-difluorobenzene (CAS 219926-41-7)
- 1,5-Dibromo-2,3-difluorobenzene (CAS 811713-09-4)
Recommended Standards
- 1,5-Dibromo-2,4-difluorobenzene (CAS 28342-75-8)
- 4-Bromo-2,6-dichloro-3-nitropyridine (CAS 1807697-58-0)
- 3-Bromo-2,4-dichloro-5-nitropyridine (CAS 850180-82-4)
- 3-Bromo-2,6-dichloro-5-nitropyridine (CAS 2091687-88-4)
- 2,6-Bis[(diphenylphosphino)methyl]pyridine (CAS 73892-45-2)
- 942037-55-0 Adipic Acid-13C6 (CAS 942037-55-0)
- 2-(3-methylcyclobutyl)acetic acid (CAS 121609-44-7)
- 5,7-Dichloro-6-isopropylpyrazolo[1,5-a]pyrimidine (CAS 1338931-96-6)
- 2-Methoxy-6-nitroaniline (CAS 16554-45-3)
- 1-(Allyloxy)-4-methoxybenzene (CAS 13391-35-0)
- 3,4-Dimethyl-N-(4-(thiophen-2-yl)thiazol-2-yl)benzamide (CAS 392246-66-1)
- 7-Ethyl-1H-indol-6-amine (CAS 145594-45-2)
- Methyl 3-(difluoromethoxy)benzoate (CAS 773873-87-3)
- Urotensin II-Related Peptide (human, mouse, rat) (CAS 342878-90-4)
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