5-Amino-N-(2-chlorophenyl)-2-(piperidin-1-yl)benzene-1-sulfonamide CAS 327072-89-9
| CAS No. | 327072-89-9 |
| Molecular Formula | C17H20ClN3O2S |
| Molecular Weight | 365.88 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-Amino-N-(2-chlorophenyl)-2-(piperidin-1-yl)benzene-1-sulfonamide.
5-Amino-N-(2-chlorophenyl)-2-(piperidin-1-yl)benzene-1-sulfonamide (CAS 327072-89-9) is a high-purity analytical reference standard with the molecular formula C17H20ClN3O2S and a molecular weight of 365.88 g/mol.
5-Amino-N-(2-chlorophenyl)-2-(piperidin-1-yl)benzene-1-sulfonamide (C17H20ClN3O2S) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C17H20ClN3O2S |
| Molecular Weight | 365.88 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Amino Standards
- 2-((4-Amino-5-(4-chlorophenyl)-4H-1,2,4-triazol-3-yl)thio)-N-cyclohexylacetamide (CAS 540498-91-7)
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- N-[4-(2-amino-1,3-thiazol-4-yl)phenyl]-4-chlorobenzene-1-sulfonamide (CAS 438030-35-4)
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Recommended Standards
- 4-(2-{[(4-chlorophenyl)methyl]sulfanyl}-6-(methoxymethyl)pyrimidin-4-yl)morpholine (CAS 478041-43-9)
- 3-Chloro-2-(4-tosylpiperazin-1-yl)aniline (CAS 892693-42-4)
- Propyl 4-((6-chloroquinazolin-4-yl)thio)piperidine-1-carboxylate (CAS 325146-08-5)
- 2-(2-(Bromomethyl)-3,4-dichlorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 1030832-48-4)
- 4-Dimethylamino 7,8-Dihydroxyflavone Dimethyl Ether (CAS 1205548-03-3)
- 4-Bromo-3-nitrobenzaldehyde (CAS 163596-75-6)
- (S)-(-)-Blebbistatin O-Benzoate (S)-3a-(Benzoyloxy)-1,2,3,3a-tetrahydro-6-methyl-1-phenyl-4H-pyrrolo[2,3-b]quinolin-4-one 1217832-61-5 (CAS 1217832-61-5)
- 2,2-Dimethyl-propanoic Acid [3-Chloro-2-[[[2-[(triphenylmethyl)amino]-5-thiazolyl]carbonyl]amino]phenyl]methyl Ester (CAS 910298-41-8)
- 2-(4-Allyl-5-morpholino-4H-1,2,4-triazol-3-yl)acetonitrile (CAS 328029-73-8)
- 2,4-Bis(2-fluorophenyl)pyridine (CAS 1214349-92-4)
- 2-(2,4,5-Trichlorophenoxy)acetonitrile (CAS 18288-25-0)
- 4,4'-Diisopropyl-1,1'-biphenyl (CAS 18970-30-4)
- 5,8-QUINOLINEDIONE (CAS 10470-83-4)
- Tau Peptide (306-317) trifluoroacetate salt (CAS 1003007-59-7)
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